Biaryl phosphane ligands in palladium‐catalyzed amination

DS Surry, SL Buchwald - Angewandte Chemie International …, 2008 - Wiley Online Library
Palladium‐catalyzed amination reactions of aryl halides have undergone rapid development
in the last 12 years, largely driven by the implementation of new classes of ligands. Biaryl …

Biarylphosphanliganden in der palladiumkatalysierten Aminierung

DS Surry, SL Buchwald - Angewandte Chemie, 2008 - Wiley Online Library
In den vergangenen 12 Jahren erfuhr die palladiumkatalysierte Aminierung von
Arylhalogeniden eine rasche Entwicklung, die durch die Einführung neuer Ligandenklassen …

Palladium-catalyzed coupling of functionalized primary and secondary amines with aryl and heteroaryl halides: two ligands suffice in most cases

D Maiti, BP Fors, JL Henderson, Y Nakamura… - Chemical …, 2011 - pubs.rsc.org
We report our studies on the use of two catalyst systems, based on the ligands BrettPhos
and RuPhos, which provide the widest scope for Pd-catalyzed C–N cross-coupling reactions …

Palladium-assisted routes to nucleosides

LA Agrofoglio, I Gillaizeau, Y Saito - Chemical reviews, 2003 - ACS Publications
Palladium-Assisted Routes to Nucleosides | Chemical Reviews ACS ACS Publications
C&EN CAS Find my institution Log In Chemical Reviews ACS Publications. Most Trusted …

Scope and mechanism of palladium-catalyzed amination of five-membered heterocyclic halides

MW Hooper, M Utsunomiya… - The Journal of Organic …, 2003 - ACS Publications
Detailed studies have been conducted to determine the activity of palladium catalysts for the
amination of five-membered heterocyclic halides and to determine the factors that control the …

Cytochrome P450 activation of arylamines and heterocyclic amines

D Kim, FP Guengerich - Annu. Rev. Pharmacol. Toxicol., 2005 - annualreviews.org
▪ Abstract Arylamines and heterocyclic arylamines (HAAs) are of particular interest because
of demonstrated carcinogenicity in animals and humans and the broad exposure to many of …

Metabolism and biomarkers of heterocyclic aromatic amines in humans

M Bellamri, SJ Walmsley, RJ Turesky - Genes and Environment, 2021 - Springer
Heterocyclic aromatic amines (HAAs) form during the high-temperature cooking of meats,
poultry, and fish. Some HAAs also arise during the combustion of tobacco. HAAs are …

Formation and analysis of heterocyclic aromatic amine–DNA adducts in vitro and in vivo

RJ Turesky, P Vouros - Journal of Chromatography B, 2004 - Elsevier
The detection and quantification of heterocyclic aromatic amine (HAA)–DNA adducts, critical
biomarkers in interspecies extrapolation of toxicity data for human risk assessment, remains …

Site-specific incorporation of N -(deoxyguanosin-8-yl)-2-acetylaminofluorene (dG-AAF) into oligonucleotides using modified 'ultra-mild' DNA synthesis

LCJ Gillet, J Alzeer, OD Schärer - Nucleic acids research, 2005 - academic.oup.com
Aromatic amino and nitro compounds are potent carcinogens found in the environment that
exert their toxic effects by reacting with DNA following metabolic activation. One important …

Understanding the coupling of heteroaromatic substrates: synthesis, structures, and reductive eliminations of heteroarylpalladium amido complexes

MW Hooper, JF Hartwig - Organometallics, 2003 - ACS Publications
Palladium furyl-and thiophenyl complexes have been studied to uncover the origin of the
difference in reactivity between coupling of five-membered heterocyclic halides and …