The influenza A M2 homotetrameric channel consists of four transmembrane (TM) and four
amphipathic helices (AHs). This viral proton channel is suggested to form clusters in the …

We present a general strategy for determining the cholesterol-binding site of eukaryotic
membrane proteins in native-like lipid membranes by NMR spectroscopy. The strategy …

The influenza A matrix 2 (M2) transmembrane protein facilitates virion release from the
infected host cell. In particular, M2 plays a role in the induction of membrane curvature …

Influenza virus assembles and buds at the plasma membrane of virus-infected cells. The
viral proteins assemble at the same site on the plasma membrane for budding to occur. This …

Amphiphilic gold nanoparticles with diameters in the 2–4 nm range are promising as
theranostic agents thanks to their spontaneous translocation through cell membranes. This …

Transmembrane peptides play important roles in many biological processes by interacting
with lipid membranes. This study investigates how the transmembrane domain of the …

Deterministic formation of membrane scission necks by protein machinery with multiplexed
functions is critical in biology. A microbial example is M2 viroporin, a proton pump from the …

Cellular attachment of viruses determines their cell tropism and species specificity. For entry,
vaccinia, the prototypic poxvirus, relies on four binding proteins and an eleven-protein entry …

A fragment of the human prion protein spanning residues 106–126 (PrP106–126)
recapitulates many essential properties of the disease-causing protein such as …

Understanding how antimicrobial peptidomimetics interact with lipid membranes is important
in battling multidrug resistant bacterial pathogens. We study the effects of a recently reported …