Conspectus Optically active nitrogen-containing compounds have attracted substantial
attention due to their ubiquity in the cores of natural products and bioactive molecules …

Conspectus Cycloaddition reactions are among the most powerful methods for the synthesis
of complex compounds. In particular, the development and application of the 1, 3-dipolar …

Catalytic asymmetric 1, 3-dipolar cycloadditions of azomethine ylides have turned out to be
one of the most efficient methods for the preparation of enantioenriched pyrrolidines. The …

Azomethine imines are considered 1, 3-dipoles of the aza-allyl type which are transient
intermediates and should be generated in situ but can also be stable and isolable …

The pyrrolidine ring is a privileged structural motif in synthetic and medicinal chemisty. This
review aims to highlight the high versatility of the catalytic asymmetric 1, 3-dipolar …

The first N-heterocyclic carbene (NHC)-catalyzed [3+ 4] cycloaddition of azomethine imines
and enals is disclosed. Oxidative catalytic remote activation of enals affords 1, 4 …

The first phosphine-catalyzed highly enantioselective [3+ 3] cycloaddition of Morita–Baylis–
Hillman carbonates with C, N-cyclic azomethine imines is described. Using a spirocyclic …

The first catalytic enantioselective construction of a 3, 3′-pyrrolidinyldispirooxindole
scaffold has been established via organocatalytic asymmetric 1, 3-dipolar cycloadditions of …

Asymmetric reactions merging organocatalysis and metal catalysis significantly broaden the
scope of organic synthesis. Nevertheless, the accomplishment of stereoselective …

Reported herein is an asymmetric [3+ 2] cycloaddition reaction of azomethine ylides with β‐
trifluoromethyl β, β‐disubstituted enones, a reaction which is enabled by a Ming‐Phos …