The devastating Ebola virus (EBOV) epidemic in West Africa in 2013–2016 accelerated the
progress of several vaccines and antivirals through clinical trials, including the replication …

Tremendous efforts are undertaken to quickly develop COVID‐19 vaccines that protect
vulnerable individuals from severe disease and thereby limit the health and socioeconomic …

Background Questions remain concerning the rapidity of immune responses and the
durability and safety of vaccines used to prevent Zaire Ebola virus disease. Methods We …

Introduction: Ebolaviruses are non-segmented negative-strand RNA viruses in the
Filoviridae family that cause a neglected infectious disease designated as Ebola virus …

The devastating Ebola virus (EBOV) outbreak in West Africa in 2013–2016 has flagged the
need for the timely development of vaccines for high-threat pathogens. To be better …

Vesicular stomatitis virus (VSV), which belongs to the Vesiculovirus genus of the family
Rhabdoviridae, is a well studied livestock pathogen and prototypic non-segmented …

Preventative vaccines are considered one of the most cost-effective and efficient means to
contain outbreaks and prevent pandemics. However, the requirements to gain licensure and …

Abstract The Brighton Collaboration Viral Vector Vaccines Safety Working Group (V3SWG)
was formed to evaluate the safety and characteristics of live, recombinant viral vector …

This report summarizes the recommendations of the Advisory Committee on Immunization
Practices (ACIP) for use of the rVSVΔG-ZEBOV-GP Ebola vaccine (Ervebo) in the United …

Summary Background During the large 2013–16 Ebola virus outbreak caused by the Zaire
Ebola virus, about 20% of cases were reported in children. This study is the first, to our …