[HTML][HTML] Nanocarriers for pancreatic cancer imaging, treatments, and immunotherapies
Pancreatic tumors are highly desmoplastic and immunosuppressive. Delivery and
distribution of drugs within pancreatic tumors are compromised due to intrinsic physical and …
distribution of drugs within pancreatic tumors are compromised due to intrinsic physical and …
Targeted delivery to tumors: multidirectional strategies to improve treatment efficiency
OM Kutova, EL Guryev, EA Sokolova, R Alzeibak… - Cancers, 2019 - mdpi.com
Malignant tumors are characterized by structural and molecular peculiarities providing a
possibility to directionally deliver antitumor drugs with minimal impact on healthy tissues and …
possibility to directionally deliver antitumor drugs with minimal impact on healthy tissues and …
Mesothelin expression in human tumors: a tissue microarray study on 12,679 tumors
S Weidemann, P Gagelmann, N Gorbokon, M Lennartz… - Biomedicines, 2021 - mdpi.com
Mesothelin (MSLN) represents an attractive molecule for targeted cancer therapies. To
identify tumors that might benefit from such therapies, tissue microarrays including 15,050 …
identify tumors that might benefit from such therapies, tissue microarrays including 15,050 …
Uptake and transfection with polymeric nanoparticles are dependent on polymer end-group structure, but largely independent of nanoparticle physical and chemical …
JC Sunshine, DY Peng, JJ Green - Molecular pharmaceutics, 2012 - ACS Publications
Development of nonviral particles for gene delivery requires a greater understanding of the
properties that enable gene delivery particles to overcome the numerous barriers to …
properties that enable gene delivery particles to overcome the numerous barriers to …
Emerging inorganic nanomaterials for pancreatic cancer diagnosis and treatment
Pancreatic cancer is a devastating disease with incidence increasing at an alarming rate
and survival not improved substantially during the past three decades. Although enormous …
and survival not improved substantially during the past three decades. Although enormous …
A novel survival-based tissue microarray of pancreatic cancer validates MUC1 and mesothelin as biomarkers
JM Winter, LH Tang, DS Klimstra, MF Brennan… - PloS one, 2012 - journals.plos.org
Background One–fifth of patients with seemingly 'curable'pancreatic ductal adenocarcinoma
(PDA) experience an early recurrence and death, receiving no definable benefit from a …
(PDA) experience an early recurrence and death, receiving no definable benefit from a …
Diphtheria in Europe: current problems and new challenges
K Zakikhany, A Efstratiou - Future microbiology, 2012 - Taylor & Francis
Diphtheria, caused by toxigenic strains of Corynebacterium diphtheriae, is an ancient
disease with high incidence and mortality that has always been characterized by epidemic …
disease with high incidence and mortality that has always been characterized by epidemic …
[HTML][HTML] Small molecule end group of linear polymer determines cell-type gene delivery efficacy
Gene delivery has the potential to treat a range of inherited and acquired diseases.
Research has primarily focused on the use of viral vectors for this purpose, due to efficient …
Research has primarily focused on the use of viral vectors for this purpose, due to efficient …
HuR status is a powerful marker for prognosis and response to gemcitabine-based chemotherapy for resected pancreatic ductal adenocarcinoma patients
NG Richards, DW Rittenhouse, B Freydin… - Annals of …, 2010 - journals.lww.com
Background: Pancreatic ductal adenocarcinoma (PDA) is a devastating disease that killed
nearly 38,000 people in the United States this past year. Objective: Treatment of PDA …
nearly 38,000 people in the United States this past year. Objective: Treatment of PDA …