A failure in redox homeostasis is a common hallmark of Alzheimer's Disease (AD) and
Parkinson's Disease (PD), two age-dependent neurodegenerative disorders (NDD), causing …

Ischemic stroke is a challenging disease with high mortality and disability rates, causing a
great economic and social burden worldwide. During ischemic stroke, ionic imbalance and …

Ischemic stroke (IS) is one of the most fatal diseases. Neuroimmunity, inflammation, and
oxidative stress play important roles in various complex mechanisms of IS. In particular, the …

Inflammation and the pro-inflammatory cytokines are associated with numerous chronic
diseases. Studies suggest that flavonoids, plant polyphenolic compound derivatives from …

Abstract The World Health Organization estimated that the proportion of older people (over
60 years) will increase from 11% to 22% during next 40 years throughout the world. With …

Brain ischemia is one of the leading causes of disability and mortality worldwide. Nitric oxide
(NO•), a molecule that is involved in the regulation of proper blood flow, vasodilation …

Neurological diseases are responsible for a large number of morbidities and mortalities in
the world. Flavonoids are phytochemicals that possess various health-promoting impacts …

Abstract Background Hexokinase-2 (HK-2) plays dual roles in glucose metabolism and
mediation of cell apoptosis, making it an attractive target for cancer therapy. Chrysin is a …

Inflammatory factors secreted by microglia play an important role in focal ischemic stroke.
The mammalian target of rapamycin (mTOR) pathway is a known regulator of immune …

Chrysin, a herbal bioactive molecule, exerts a plethora of pharmacological effects, including
anti-oxidant, anti-inflammatory, neuroprotective, and anti-cancer. A growing body of …