The Alzheimer's Disease Neuroimaging Initiative (ADNI) beginning in October 2004, is a 6- year research project that studies changes of cognition, function, brain structure and …
Abstract The Alzheimer's Disease Neuroimaging Initiative (ADNI) is an ongoing, longitudinal, multicenter study designed to develop clinical, imaging, genetic, and …
LR Clark, DM Schiehser, GH Weissberger… - Journal of the …, 2012 - cambridge.org
Decline in executive function has been noted in the prodromal stage of Alzheimer's disease (AD) and may presage more global cognitive declines. In this prospective longitudinal study …
Background The three core pathologies of Alzheimer's disease (AD) are amyloid pathology, tau pathology, and neurodegeneration. Biomarkers exist for each. Neurodegeneration is …
KJ Bangen, AJ Jak, DM Schiehser… - Journal of the …, 2010 - cambridge.org
There is increasing consensus regarding the importance of operationally defining and measuring functional decline in mild cognitive impairment (MCI). However, few studies have …
Using cluster analysis Libon et al.(2010) found three verbal serial list-learning profiles involving delay memory test performance in patients with mild cognitive impairment (MCI) …
Background Decline in episodic memory is one of the hallmark features of Alzheimer's disease (AD) and is also a defining feature of amnestic Mild Cognitive Impairment (MCI) …
Objective: To evaluate whether ratings on Clinical Dementia Rating (CDR) items related to instrumental activities of daily living (IADL) are associated with cognitive or brain …
Mild cognitive impairment (MCI) and Alzheimer's disease (AD) are associated with a progressive loss of cognitive abilities. In the present report, we assessed the relationship of …