In the current “genomic era” the number of identified genes is growing exponentially.
However, the biological function of a large number of the corresponding proteins is still …

The dynamic nature of technological developments invites us to rethink the learning spaces.
In this context, science education can be enriched by the contribution of new computational …

Epidermal growth factor (EGF) is known to play key roles in skin regeneration and wound-
healing. Here, we demonstrate that Pep2-YAC, a tripeptide covering residues 29-31 in the B …

The epidermal growth factor receptor (EGFR) is a membrane-anchored tyrosine kinase that
is able to selectively respond to multiple extracellular stimuli. Previous studies have …

Enzyme interactions with ligands are crucial for various biochemical reactions governing life.
Over many years attempts to identify these residues for biotechnological manipulations have …

Background Comparative analysis of homologous sequences enables the understanding of
evolutionary patterns at the molecular level, unraveling the functional constraints that …

Proteins participate in every important aspect of known living systems. The amino acid
sequence of a protein contains information about the physicochemical properties, the …

With few exceptions protein functions depend sensitively upon their interactions with other
biomolecules. Thus, the surface of a protein is of particular interest for function annotation …

The Epidermal Growth Factor Receptor (EGFR) is a membrane-anchored tyrosine kinase
that 19 is able to respond to multiple extra-cellular stimuli in a selective way. Previous …

Neutral amino acids are essential for protein synthesis, energy homeostasis, and many vital
biochemical pathways. As several neutral amino acids are essential and cannot be …