γδ T cells: origin and fate, subsets, diseases and immunotherapy

Y Hu, Q Hu, Y Li, L Lu, Z Xiang, Z Yin… - … and Targeted Therapy, 2023 - nature.com
The intricacy of diseases, shaped by intrinsic processes like immune system exhaustion and
hyperactivation, highlights the potential of immune renormalization as a promising strategy …

Regulatory T cells in the face of the intestinal microbiota

D Ramanan, A Pratama, Y Zhu, O Venezia… - Nature Reviews …, 2023 - nature.com
Regulatory T cells (Treg cells) are key players in ensuring a peaceful coexistence with
microorganisms and food antigens at intestinal borders. Startling new information has …

Maternal anxiety, depression and stress affects offspring gut microbiome diversity and bifidobacterial abundances

JD Galley, L Mashburn-Warren, LC Blalock… - Brain, Behavior, and …, 2023 - Elsevier
Uncovering mechanisms underlying fetal programming during pregnancy is of critical
importance. Atypical neurodevelopment during the pre-and immediate postnatal period has …

Nonresolving inflammation redux

C Nathan - Immunity, 2022 - cell.com
Nonresolving inflammation contributes to many diseases, including COVID-19 in its fatal and
long forms. Our understanding of inflammation is rapidly evolving. Like the immune system …

[PDF][PDF] Maternal inflammation and its ramifications on fetal neurodevelopment

HK Kwon, GB Choi, JR Huh - Trends in immunology, 2022 - cell.com
Exposure to heightened inflammation in pregnancy caused by infections or other
inflammatory insults has been associated with the onset of neurodevelopmental and …

Gastrointestinal and brain barriers: unlocking gates of communication across the microbiota–gut–brain axis

MR Aburto, JF Cryan - Nature Reviews Gastroenterology & Hepatology, 2024 - nature.com
Crosstalk between gut and brain has long been appreciated in health and disease, and the
gut microbiota is a key player in communication between these two distant organs. Yet, the …

Interleukin-17 as a key player in neuroimmunometabolism

A Douglas, B Stevens, L Lynch - Nature metabolism, 2023 - nature.com
Abstract In mammals, interleukin (IL)-17 cytokines are produced by innate and adaptive
lymphocytes. However, the IL-17 family has widespread expression throughout evolution …

[HTML][HTML] Immunogenetics of autism spectrum disorder: a systematic literature review

M Arenella, R Matuleviciute, R Tamouza… - Brain, Behavior, and …, 2023 - Elsevier
The aetiology of autism spectrum disorder (ASD) is complex and, partly, accounted by
genetic factors. Nonetheless, the genetic underpinnings of ASD are poorly defined. The …

Inflammatory cytokines and prenatal depression: Is there a mediating role of maternal gut microbiota?

Q Fang, Y Tu, X Fan, T Zang, N Wu, T Qiu, Y Li… - Journal of Psychiatric …, 2023 - Elsevier
Objective The mechanism of levels of inflammatory cytokines that affects brain function and
mood through gut microbiota has not been fully elucidated. This study aimed to investigate …

[HTML][HTML] The communication mechanism of the gut-brain axis and its effect on central nervous system diseases: A systematic review

S Lu, Q Zhao, Y Guan, Z Sun, W Li, S Guo… - Biomedicine & …, 2024 - Elsevier
Gut microbiota is involved in intricate and active metabolic processes the host's brain
function, especially its role in immune responses, secondary metabolism, and symbiotic …