[PDF][PDF] Current topic: glucose transporters in the human placenta

NP Illsley - Placenta, 2000 - researchgate.net
The availability of antibodies and cDNA probes specific for the various members of the
facilitated-diffusion glucose transporter (GLUT) family has enabled researchers to obtain a …

Scrutinising the regulators of syncytialization and their expression in pregnancy-related conditions

MA Costa - Molecular and cellular endocrinology, 2016 - Elsevier
The placenta is important for the success of gestation and foetal development. In fact, this
specialized pregnancy organ is essential for foetal nourishment, support, and protection. In …

Hypoxic upregulation of glucose transporters in BeWo choriocarcinoma cells is mediated by hypoxia-inducible factor-1

MU Baumann, S Zamudio… - American Journal of …, 2007 - journals.physiology.org
Placental hypoxia has been implicated in pregnancy pathologies, including fetal growth
restriction and preeclampsia; however, the mechanism by which the trophoblast cell …

Differential effects of inducers of syncytialization and apoptosis on BeWo and JEG-3 choriocarcinoma cells

S Al-Nasiry, B Spitz, M Hanssens, C Luyten… - Human …, 2006 - academic.oup.com
BACKGROUND: The interactions of trophoblasts with the cytokine network at the
fetomaternal interface determine the pathway the cell undertakes, eg proliferation …

Selective cholesteryl ester uptake from high density lipoprotein by human first trimester and term villous trophoblast cells

C Wadsack, A Hammer, S Levak-Frank, G Desoye… - Placenta, 2003 - Elsevier
As villous trophoblast does represent the contact zone between foetal and maternal tissues,
the present in vitro study was aimed at investigating cholesterol supply from human high …

The 5-HT2A serotonin receptor enhances cell viability, affects cell cycle progression and activates MEK–ERK1/2 and JAK2–STAT3 signalling pathways in human …

T Oufkir, M Arseneault, JT Sanderson, C Vaillancourt - Placenta, 2010 - Elsevier
Previous results from our group have demonstrated the expression of the 5-HT2A receptor
and a mitogenic effect of serotonin in human trophoblast. The objectives of the present study …

Trophoblast cell fusion and differentiation are mediated by both the protein kinase C and a pathways

W Omata, WE Ackerman IV, DD Vandre… - PLoS One, 2013 - journals.plos.org
The syncytiotrophoblast of the human placenta is an epithelial barrier that interacts with
maternal blood and is a key for the transfer of nutrients and other solutes to the developing …

Human embryonic stem cells as models for trophoblast differentiation

LC Schulz, T Ezashi, P Das, SD Westfall, KA Livingston… - Placenta, 2008 - Elsevier
Trophectoderm is specified from pluripotent blastomeres at some time prior to blastocyst
formation. Proliferating cytotrophoblast derived from trophectoderm is the forerunner of the …

Adhesion of trophoblast to uterine epithelium as related to the state of trophoblast differentiation: in vitro studies using cell lines

HP Hohn, M Linke, HW Denker - Molecular Reproduction and …, 2000 - Wiley Online Library
At the initial phase of embryo implantation, the trophoblast must have acquired competence
for adhesion to the uterine epithelium, a condition whose cell biological basis is far from …

Inhibition of cytotrophoblastic (JEG-3) cell invasion by interleukin 12 involves an interferon γ-mediated pathway

S Karmakar, R Dhar, C Das - Journal of Biological Chemistry, 2004 - ASBMB
Trophoblast invasion, like tumor invasion, shares common biochemical mechanisms.
However, in contrast to tumor invasion of a host tissue, trophoblastic invasion during …