Variants within non-coding genomic regions can greatly affect disease. In recent years,
increasing focus has been given to these variants, and how they can alter regulatory …

For more than two decades, the UCSC Genome Browser database (https://genome. ucsc.
edu) has provided high-quality genomics data visualization and genome annotations to the …

A major challenge in understanding gene regulation is the unequivocal identification of
enhancer elements and uncovering their connections to genes. We present GeneHancer, a …

DNA is fundamentally important for all cellular organisms due to its role as a store of
hereditary genetic information. The precise and accurate regulation of gene transcription …

Despite the high prevalence of both cervico-vaginal human papillomavirus (HPV) infection
and bacterial vaginosis (BV) worldwide, their causal relationship remains unclear. While BV …

We present an update of the Eukaryotic Promoter Database EPD (http://epd. vital-it. ch),
more specifically on the EPDnew division, which contains comprehensive organisms …

Human brains vary across people and over time; such variation is not yet understood in
cellular terms. Here we describe a relationship between people's cortical neurons and …

With concurrent global epidemics of chronic pain and opioid use disorders, there is a critical
need to identify, target and manipulate specific cell populations expressing the mu-opioid …

Single-cell transcriptomics (scRNA-seq) has revolutionized the understanding of the spatial
architecture of tissue structure and function. Advancing the" transcript-centric" view of scRNA …

Ferroptosis is a regulated cell death modality that occurs upon iron-dependent lipid
peroxidation. Recent research has identified many regulators that induce or inhibit …