Hamsters as a model of severe acute respiratory syndrome coronavirus-2

AM Braxton, PS Creisher, CA Ruiz-Bedoya… - Comparative …, 2021 - ingentaconnect.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of coronavirus
disease 2019 (COVID-19), rapidly spread across the world in late 2019, leading to a …

[HTML][HTML] Compromised gastrointestinal integrity in pigtail macaques is associated with increased microbial translocation, immune activation, and IL-17 production in …

NR Klatt, LD Harris, CL Vinton, H Sung, JA Briant… - Mucosal …, 2010 - Elsevier
Pigtail macaques (PTMs) rapidly progress to AIDS after simian immunodeficiency virus (SIV)
infection. Given the strong association between human immunodeficiency virus (HIV) and …

HIV and SIV associated thrombocytopenia: an expanding role for platelets in the pathogenesis of HIV

KAM Pate, JL Mankowski - Drug discovery today: disease mechanisms, 2011 - Elsevier
Thrombocytopenia is common in HIV and SIV infection, and is often associated with disease
progression. HIV and SIV-associated thrombocytopenia arise through multiple mechanisms …

[HTML][HTML] IL-21 and probiotic therapy improve Th17 frequencies, microbial translocation, and microbiome in ARV-treated, SIV-infected macaques

AM Ortiz, ZA Klase, SR DiNapoli, I Vujkovic-Cvijin… - Mucosal …, 2016 - Elsevier
Increased mortality in antiretroviral (ARV)-treated, HIV-infected individuals has been
attributed to persistent immune dysfunction, in part due to abnormalities at the …

Characterization of a new simian immunodeficiency virus strain in a naturally infected Pan troglodytes troglodyteschimpanzee with AIDS related symptoms

L Etienne, E Nerrienet, M LeBreton, GT Bibila… - Retrovirology, 2011 - Springer
Background Data on the evolution of natural SIV infection in chimpanzees (SIVcpz) and on
the impact of SIV on local ape populations are only available for Eastern African …

Modeling HIV-1 induced neuroinflammation in mice: role of platelets in mediating blood-brain barrier dysfunction

LD Jones, JW Jackson, SB Maggirwar - PLoS One, 2016 - journals.plos.org
The number of HIV-1 positive individuals developing some form of HIV-associated
neurocognitive disorder (HAND) is increasing. In these individuals, the integrity of the blood …

Dynamics of simian immunodeficiency virus SIVmac239 infection in pigtail macaques

NR Klatt, LA Canary, TH Vanderford, CL Vinton… - Journal of …, 2012 - Am Soc Microbiol
Pigtail macaques (PTM) are an excellent model for HIV research; however, the dynamics of
simian immunodeficiency virus (SIV) SIVmac239 infection in PTM have not been fully …

Rate of AIDS progression is associated with gastrointestinal dysfunction in simian immunodeficiency virus–infected pigtail macaques

LA Canary, CL Vinton, DR Morcock… - The Journal of …, 2013 - journals.aai.org
During HIV/SIV infection, mucosal immune system dysfunction and systemic immune
activation are associated with progression to AIDS; however, it is unclear to what extent pre …

Effect of single housing on innate immune activation in immunodeficiency virus–infected pigtail macaques (Macaca nemestrina) as a model of psychosocial stress in …

N Castell, SM Guerrero-Martin, LH Rubin… - Psychosomatic …, 2022 - journals.lww.com
Objective Simian immunodeficiency virus (SIV) infection of macaques recapitulates many
aspects of HIV pathogenesis and is similarly affected by both genetic and environmental …

Elite control, gut CD4 T cell sparing, and enhanced mucosal T cell responses in Macaca nemestrina infected by a simian immunodeficiency virus lacking a gp41 …

MW Breed, SE Elser, W Torben, APO Jordan… - Journal of …, 2015 - Am Soc Microbiol
ABSTRACT Deletion of Gly-720 and Tyr-721 from a highly conserved GYxxØ trafficking
signal in the SIVmac239 envelope glycoprotein cytoplasmic domain, producing a virus …