[HTML][HTML] Searching images for consensus: can AI remove observer variability in pathology?

HR Tizhoosh, P Diamandis, CJV Campbell… - The American journal of …, 2021 - Elsevier
One of the major obstacles in reaching diagnostic consensus is observer variability. With the
recent success of artificial intelligence, particularly the deep networks, the question emerges …

Empowering renal cancer management with AI and digital pathology: Pathology, diagnostics and prognosis

E Ivanova, A Fayzullin, V Grinin, D Ermilov… - Biomedicines, 2023 - mdpi.com
Renal cell carcinoma is a significant health burden worldwide, necessitating accurate and
efficient diagnostic methods to guide treatment decisions. Traditional pathology practices …

Deep learning can predict survival directly from histology in clear cell renal cell carcinoma

F Wessels, M Schmitt, E Krieghoff-Henning, JN Kather… - PLoS …, 2022 - journals.plos.org
For clear cell renal cell carcinoma (ccRCC) risk-dependent diagnostic and therapeutic
algorithms are routinely implemented in clinical practice. Artificial intelligence-based image …

HAVOC: Small-scale histomic mapping of cancer biodiversity across large tissue distances using deep neural networks

A Dent, K Faust, KHB Lam, N Alhangari, AJ Leon… - Science …, 2023 - science.org
Intratumoral heterogeneity can wreak havoc on current precision medicine strategies
because of challenges in sufficient sampling of geographically separated areas of …

Intratumoral resolution of driver gene mutation heterogeneity in renal cancer using deep learning

PH Acosta, V Panwar, V Jarmale, A Christie, J Jasti… - Cancer research, 2022 - AACR
Intratumoral heterogeneity arising from tumor evolution poses significant challenges
biologically and clinically. Dissecting this complexity may benefit from deep learning (DL) …

Multi‐omics‐based autophagy‐related untypical subtypes in patients with cerebral amyloid pathology

JC Park, N Barahona‐Torres, SY Jang… - Advanced …, 2022 - Wiley Online Library
Recent multi‐omics analyses paved the way for a comprehensive understanding of
pathological processes. However, only few studies have explored Alzheimer's disease (AD) …

Incorporating intratumoral heterogeneity into weakly-supervised deep learning models via variance pooling

I Carmichael, AH Song, RJ Chen… - … Conference on Medical …, 2022 - Springer
Supervised learning tasks such as cancer survival prediction from gigapixel whole slide
images (WSIs) are a critical challenge in computational pathology that requires modeling …

Integrating computational pathology and proteomics to address tumor heterogeneity

A Dent, P Diamandis - The Journal of Pathology, 2022 - Wiley Online Library
Despite numerous advances in our molecular understanding of cancer biology, success in
precision medicine trials has remained elusive for many malignancies. Emerging evidence …

Clinical application of digital and computational pathology in renal cell carcinoma: a systematic review

ZE Khene, SF Kammerer-Jacquet, P Bigot… - European Urology …, 2023 - Elsevier
Context Computational pathology is a new interdisciplinary field that combines traditional
pathology with modern technologies such as digital imaging and machine learning to better …

[HTML][HTML] Selection, visualization, and interpretation of deep features in lung adenocarcinoma and squamous cell carcinoma

T Dehkharghanian, S Rahnamayan, A Riasatian… - The American Journal of …, 2021 - Elsevier
Although deep learning networks applied to digital images have shown impressive results
for many pathology-related tasks, their black-box approach and limitation in terms of …