Emerging Concern for Silver Nanoparticle Resistance in Acinetobacter baumannii and Other Bacteria

O McNeilly, R Mann, M Hamidian… - Frontiers in …, 2021 - frontiersin.org
The misuse of antibiotics combined with a lack of newly developed ones is the main
contributors to the current antibiotic resistance crisis. There is a dire need for new and …

Fighting Antibiotic‐Resistant Bacteria: Promising Strategies Orchestrated by Molecularly Imprinted Polymers

B Tse Sum Bui, T Auroy, K Haupt - … Chemie International Edition, 2022 - Wiley Online Library
Infections caused by antibiotic‐resistant bacteria are difficult and sometimes impossible to
treat, making them one of the major public health problems of our time. We highlight how …

Birth mode is associated with earliest strain-conferred gut microbiome functions and immunostimulatory potential

L Wampach, A Heintz-Buschart, JV Fritz… - Nature …, 2018 - nature.com
The rate of caesarean section delivery (CSD) is increasing worldwide. It remains unclear
whether disruption of mother-to-neonate transmission of microbiota through CSD occurs and …

[HTML][HTML] Cell-free synthetic biology: Engineering in an open world

Y Lu - Synthetic and systems biotechnology, 2017 - Elsevier
Cell-free synthetic biology emerges as a powerful and flexible enabling technology that can
engineer biological parts and systems for life science applications without using living cells …

Vaccines, adjuvants and key factors for mucosal immune response

VA Correa, AI Portilho, E De Gaspari - Immunology, 2022 - Wiley Online Library
Vaccines are the most effective tool to control infectious diseases, which provoke significant
morbidity and mortality rates. Most vaccines are administered through the parenteral route …

In-silico design of a multivalent epitope-based vaccine against Candida auris

N Akhtar, A Joshi, V Kaushik, M Kumar… - Microbial …, 2021 - Elsevier
Candida auris is a rapidly emerging human pathogenic fungus with a high mortality rate.
Recent report suggests that the new clinical isolates are showing resistance to the major …

Protein-based adjuvants for vaccines as immunomodulators of the innate and adaptive immune response: Current knowledge, challenges, and future opportunities

DA Díaz-Dinamarca, ML Salazar, BN Castillo… - Pharmaceutics, 2022 - mdpi.com
New-generation vaccines, formulated with subunits or nucleic acids, are less immunogenic
than classical vaccines formulated with live-attenuated or inactivated pathogens. This …

Advances and challenges in cell-free incorporation of unnatural amino acids into proteins

W Gao, E Cho, Y Liu, Y Lu - Frontiers in pharmacology, 2019 - frontiersin.org
Incorporation of unnatural amino acids (UNAAs) into proteins currently is an active biological
research area for various fundamental and applied science. In this context, cell-free …

Engineered macromolecular Toll-like receptor agents and assemblies

BAJ Hoffman, EA Pumford, AI Enueme, KL Fetah… - Trends in …, 2023 - cell.com
Macromolecular Toll-like receptor (TLR) agents have been utilized as agonists and
inhibitors in preclinical and clinical settings. These agents interface with the TLR class of …

Biotechnology approaches to produce potent, self-adjuvanting antigen-adjuvant fusion protein subunit vaccines

PM Moyle - Biotechnology advances, 2017 - Elsevier
Traditional vaccination approaches (eg live attenuated or killed microorganisms) are among
the most effective means to prevent the spread of infectious diseases. These approaches …