Keratin 6, 16 and 17—critical barrier alarmin molecules in skin wounds and psoriasis

X Zhang, M Yin, L Zhang - Cells, 2019 - mdpi.com
Located at the skin surface, keratinocytes (KCs) are constantly exposed to external stimuli
and are the first responders to invading pathogens and injury. Upon skin injury, activated …

The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells

R Moll, WW Franke, DL Schiller, B Geiger, R Krepler - Cell, 1982 - Elsevier
A large proportion of the cytoplasm of vertebrate cells, normal or transformed, is represented
by components of the cytoskeleton, including actin-containing microfilaments, tubulin …

The human keratins: biology and pathology

R Moll, M Divo, L Langbein - Histochemistry and cell biology, 2008 - Springer
The keratins are the typical intermediate filament proteins of epithelia, showing an
outstanding degree of molecular diversity. Heteropolymeric filaments are formed by pairing …

Differentiation-related expression of a major 64K corneal keratin in vivo and in culture suggests limbal location of corneal epithelial stem cells.

A Schermer, S Galvin, TT Sun - The Journal of cell biology, 1986 - rupress.org
In this paper we present keratin expression data that lend strong support to a model of
corneal epithelial maturation in which the stem cells are located in the limbus, the …

Purification, Characterization, and in vitro Differentiation of Cytotrophoblasts from Human Term Placentae

HJ KLIMAN, JE Nestler, E Sermasi, JM SANGER… - …, 1986 - academic.oup.com
Highly purified functional cytotrophoblasts have been prepared from human term placentae
by adding a Percoll gradient centrifugation step to a standard trypsin-DNase dispersion …

Keratin expression in human tissues and neoplasms

PG Chu, LM Weiss - Histopathology, 2002 - Wiley Online Library
Keratin expression in human tissues and neoplasms Keratin filaments constitute type I and
type II intermediate filaments (IFs), with at least 20 subtypes named keratin 1–20. Since …

Location and clonal analysis of stem cells and their differentiated progeny in the human ocular surface

G Pellegrini, O Golisano, P Paterna… - The Journal of cell …, 1999 - rupress.org
We have analyzed the proliferative and differentiation potential of human ocular
keratinocytes. Holoclones, meroclones, and paraclones, previously identified in skin …

Cytokeratin 20 in human carcinomas. A new histodiagnostic marker detected by monoclonal antibodies.

R Moll, A Löwe, J Laufer, WW Franke - The American journal of …, 1992 - ncbi.nlm.nih.gov
The authors have recently identified a new cytokeratin (CK) polypeptide, CK 20, whose
expression is almost entirely confined to the gastric and intestinal epithelium, urothelium …

Synaptophysin: a marker protein for neuroendocrine cells and neoplasms.

B Wiedenmann, WW Franke, C Kuhn… - Proceedings of the …, 1986 - National Acad Sciences
Synaptophysin is an integral membrane glycoprotein (Mr 38,000) that occurs in presynaptic
vesicles of neurons and in similar vesicles of the adrenal medulla. By using a monoclonal …

Intermediate filaments at the junction of mechanotransduction, migration, and development

R Sanghvi-Shah, GF Weber - Frontiers in cell and developmental …, 2017 - frontiersin.org
Mechanically induced signal transduction has an essential role in development. Cells
actively transduce and respond to mechanical signals and their internal architecture must …