Increasing evidence suggests that the failure of clinical antidepressants may be related with
neuroinflammation. The NOD-, LRR-and pyrin domain-containing protein 3 (NLRP3) …

Sodium-glucose co-transporter 2 inhibitors, also known as gliflozins, were developed as a
novel class of anti-diabetic agents that promote glycosuria through the prevention of glucose …

There is a strong medical need to develop suitable biomarkers to improve the diagnosis and
treatment of depression, particularly in predicting response to certain therapeutic …

Cadmium is an environmental contaminant associated with marked neurotoxicity and
cognitive impairment. Linagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, has …

Major depressive disorder (MDD) is a common mental disorder with high morbidity. Stress
negatively affects for MDD development, whereby transport of stress‐induced inflammatory …

Background Alcohol use disorders result from repeated binge and chronic alcohol
consumption followed by negative effects, such as anxiety, upon cessation. This process is …

Depression, a major public health problem, imposes a significant economic burden on
society. Recent studies have gradually unveiled the important role of neuroinflammation in …

Depression holds the title of the largest contributor to worldwide disability, with the numbers
expected to continue growing. Currently, there are neither reliable biomarkers for the …

This review explores the pivotal role of the nucleotide-binding oligomerization domain
(NOD)-like receptor protein 3 (NLRP3) inflammasome in the pathogenesis of diabetes and …

Diabetic kidney disease (DKD) is one of the most important comorbidities for patients with
diabetes, and its incidence has exceeded one tenth, with an increasing trend. Studies have …