Evaluation and management of the child and adult with Fontan circulation: a scientific statement from the American Heart Association

J Rychik, AM Atz, DS Celermajer, BJ Deal… - Circulation, 2019 - Am Heart Assoc
It has been 50 years since Francis Fontan pioneered the operation that today bears his
name. Initially designed for patients with tricuspid atresia, this procedure is now offered for a …

The Fontan circulation after 45 years: update in physiology

M Gewillig, SC Brown - Heart, 2016 - heart.bmj.com
The Fontan operation was first performed in 1968. Since then, this operation has been
performed on thousands of patients worldwide. Results vary from very good for many …

[图书][B] Comprehensive surgical management of congenital heart disease

R Jonas - 2002 - books.google.com
The management of congenital heart disease has changed dramatically over the last 15
years and continues to evolve at a rapid pace. More than ever before contemporary practice …

Bosentan improves exercise capacity in adolescents and adults after Fontan operation: the TEMPO (treatment with endothelin receptor antagonist in Fontan patients, a …

A Hebert, UR Mikkelsen, U Thilen, L Idorn, AS Jensen… - Circulation, 2014 - Am Heart Assoc
Background—The Fontan procedure has improved survival in children with functionally
univentricular hearts. With time, however, complications such as reduced exercise capacity …

[HTML][HTML] The relentless effects of the Fontan paradox

J Rychik - Seminars in Thoracic and Cardiovascular Surgery …, 2016 - Elsevier
The Fontan operation is the anticipated palliative strategy for children born with single-
ventricle type of congenital heart disease. As a result of important circulatory limitations, a …

Impact of oral sildenafil on exercise performance in children and young adults after the Fontan operation: a randomized, double-blind, placebo-controlled, crossover …

DJ Goldberg, B French, MG McBride, BS Marino… - Circulation, 2011 - Am Heart Assoc
Background—Children and young adults with single-ventricle physiology have abnormal
exercise capacity after the Fontan operation. A medication capable of decreasing pulmonary …

Failure of the fontan circulation

M Gewillig, DJ Goldberg - Heart failure clinics, 2014 - heartfailure.theclinics.com
A normal mammalian cardiovascular system consists of a double circuit, pulmonary and
systemic, connected in series and powered by a double pump. In the absence of congenital …

Results of the FUEL Trial

DJ Goldberg, V Zak, BH Goldstein, KR Schumacher… - Circulation, 2020 - Am Heart Assoc
Background: The Fontan operation creates a total cavopulmonary connection, a circulation
in which the importance of pulmonary vascular resistance is magnified. Over time, this …

MELD-XI score and cardiac mortality or transplantation in patients after Fontan surgery

GE Assenza, DA Graham, MJ Landzberg, AM Valente… - Heart, 2013 - heart.bmj.com
Objective The Fontan operation is a staged palliation for complex congenital heart disease
and single ventricle physiology. Perioperative survivors of the Fontan operation experience …

Four decades of Fontan palliation

MR De Leval, JE Deanfield - Nature Reviews Cardiology, 2010 - nature.com
The Fontan palliation was introduced in 1968 to treat cardiac malformations unsuitable for
biventricular repair. This procedure has transformed the surgical management of congenital …