A systematic review and quantitative synthesis of the long-term psychiatric sequelae of pediatric autoimmune encephalitis

L Nguyen, JH Yang, S Goyal, N Irani… - Journal of Affective …, 2022 - Elsevier
Background Long-term neuropsychiatric sequelae of autoimmune encephalitis (AE) remain
understudied, particularly in pediatric-onset AE. We aimed to synthesize the published data …

Autoimmune diseases: targets, biology, and drug discovery

S Li, Y Wu, J Chen, S Shen, J Duan… - Acta Pharmacologica …, 2024 - nature.com
Autoimmune diseases (AIDs) arise from a breakdown in immunological self-tolerance,
wherein the adaptive immune system mistakenly attacks healthy cells, tissues and organs …

Translational imaging of TSPO reveals pronounced innate inflammation in human and murine CD8 T cell–mediated limbic encephalitis

M Gallus, W Roll, A Dik, C Barca, B Zinnhardt… - Science …, 2023 - science.org
Autoimmune limbic encephalitis (ALE) presents with new-onset mesial temporal lobe
seizures, progressive memory disturbance, and other behavioral and cognitive changes …

[HTML][HTML] Review and meta-analysis of neuropsychological findings in autoimmune limbic encephalitis with autoantibodies against LGI1, CASPR2, and GAD65 and …

C Mueller, S Elben, GS Day, P Alves, J Hebert… - Clinical Neurology and …, 2023 - Elsevier
Objectives It is assumed that autoimmune limbic encephalitis (ALE) demonstrates distinct
neuropsychological manifestations with differential responses to immunotherapy according …

[18F] FDG brain PET and clinical symptoms in different autoantibodies of autoimmune encephalitis: a systematic review

F Nabizadeh, E Ramezannezhad, A Sardaripour… - Neurological …, 2022 - Springer
Introduction Autoimmune encephalitis (AE) is caused by the antibodies that target receptors
and intracellular or surface proteins. To achieve the appropriate therapeutic results, early …

Neuropsychological evaluations in limbic encephalitis

JA Witt, C Helmstaedter - Brain Sciences, 2021 - mdpi.com
Limbic encephalitis (LE) can cause dynamic and permanent impairment of cognition and
behavior. In clinical practice, the question arises as to which cognitive and behavioral …

[HTML][HTML] Dysfunction of the NMDA Receptor in the Pathophysiology of Schizophrenia and/or the Pathomechanisms of Treatment-Resistant Schizophrenia

R Okubo, M Okada, E Motomura - Biomolecules, 2024 - mdpi.com
For several decades, the dopamine hypothesis contributed to the discovery of numerous
typical and atypical antipsychotics and was the sole hypothesis for the pathophysiology of …

A juvenile mouse model of anti-N-methyl-D-aspartate receptor encephalitis by active immunization

S He, C Sun, Q Zhu, L Li, J Huang, G Wu… - Frontiers in Molecular …, 2023 - frontiersin.org
Introduction Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a common
autoimmune encephalitis, and it is associated with psychosis, dyskinesia, and seizures. Anti …

Human-derived monoclonal autoantibodies as interrogators of cellular proteotypes in the brain

ML Baum, CM Bartley - Trends in Neurosciences, 2024 - cell.com
A major aim of neuroscience is to identify and model the functional properties of neural cells
whose dysfunction underlie neuropsychiatric illness. In this article, we propose that human …

Infodemiology of autoimmune encephalitis, autoimmune seizures, and autoimmune epilepsy: An analysis of online search behavior using Google Trends

KT Roberto, RDG Jamora, KMC Moalong, AI Espiritu - Epilepsy & Behavior, 2022 - Elsevier
Background Patients and their caregivers, including clinicians and educators, use web-
based search engines to access healthcare-related information from the internet. Online …