The roles of serotonin in neuropsychiatric disorders
The serotonergic system extends throughout the central nervous system (CNS) and the
gastrointestinal (GI) tract. In the CNS, serotonin (5-HT, 5-hydroxytryptamine) modulates a …
gastrointestinal (GI) tract. In the CNS, serotonin (5-HT, 5-hydroxytryptamine) modulates a …
[HTML][HTML] Depression and adult neurogenesis: Positive effects of the antidepressant fluoxetine and of physical exercise
Of wide interest for health is the relation existing between depression, a very common
psychological illness, accompanied by anxiety and reduced ability to concentrate, and adult …
psychological illness, accompanied by anxiety and reduced ability to concentrate, and adult …
Neurobiological links between depression and AD: the role of TGF-β1 signaling as a new pharmacological target
In the last several years a large number of studies have demonstrated the neurobiological
and clinical continuum between depression and Alzheimer's disease (AD). Depression is a …
and clinical continuum between depression and Alzheimer's disease (AD). Depression is a …
Mechanism of depression as a risk factor in the development of Alzheimer's disease: the function of AQP4 and the glymphatic system
M Xia, L Yang, G Sun, S Qi, B Li - Psychopharmacology, 2017 - Springer
Background Many studies have indicated that a history of depression increases the risk of
developing Alzheimer's disease (AD); however, the potential pathogenestic mechanism by …
developing Alzheimer's disease (AD); however, the potential pathogenestic mechanism by …
Antioxidant activity of fluoxetine and vortioxetine in a non-transgenic animal model of alzheimer's disease
G Caruso, M Grasso, A Fidilio, SA Torrisi… - Frontiers in …, 2021 - frontiersin.org
Depression is a risk factor for the development of Alzheimer's disease (AD). A
neurobiological and clinical continuum exists between AD and depression, with …
neurobiological and clinical continuum exists between AD and depression, with …
Protective effects of antidepressant citalopram against abnormal APP processing and amyloid beta-induced mitochondrial dynamics, biogenesis, mitophagy and …
The purpose of this study is to study the neuroprotective role of selective serotonin reuptake
inhibitor (SSRI), citalopram, against Alzheimer's disease (AD). Multiple SSRIs, including …
inhibitor (SSRI), citalopram, against Alzheimer's disease (AD). Multiple SSRIs, including …
Fluoxetine and Vortioxetine Reverse Depressive-Like Phenotype and Memory Deficits Induced by Aβ1-42 Oligomers in Mice: A Key Role of Transforming Growth …
SA Torrisi, F Geraci, MR Tropea, M Grasso… - Frontiers in …, 2019 - frontiersin.org
Depression is a risk factor for the development of Alzheimer's disease (AD), and the
presence of depressive symptoms significantly increases the conversion of mild cognitive …
presence of depressive symptoms significantly increases the conversion of mild cognitive …
Selective serotonin reuptake inhibitors and Alzheimer's disease
Given the failure to develop disease-modifying therapies for Alzheimer's disease (AD),
strategies aiming at preventing or delaying the onset of the disease are being prioritized …
strategies aiming at preventing or delaying the onset of the disease are being prioritized …
Irisin exerts neuroprotective effects on cultured neurons by regulating astrocytes
Neurons suffer detrimental effects from β‐amyloid toxicity in Alzheimer's disease. The
exercise hormone, irisin, is found to induce a neuroprotective gene program and facilitates …
exercise hormone, irisin, is found to induce a neuroprotective gene program and facilitates …
Antidepressants in Alzheimer's disease: a focus on the role of mirtazapine
AS Correia, N Vale - Pharmaceuticals, 2021 - mdpi.com
Mirtazapine belongs to the category of antidepressants clinically used mainly in major
depressive disorder but also used in obsessive-compulsive disorders, generalized anxiety …
depressive disorder but also used in obsessive-compulsive disorders, generalized anxiety …