Advances in thiosemicarbazone metal complexes as anti-lung cancer agents

XG Bai, Y Zheng, J Qi - Frontiers in Pharmacology, 2022 - frontiersin.org
The great success of cisplatin as a chemotherapeutic agent considerably increased
research efforts in inorganic biochemistry to identify more metallic drugs having the potential …

A mini review on isatin, an anticancer scaffold with potential activities against neglected tropical diseases (NTDs)

S Chowdhary, Shalini, A Arora, V Kumar - Pharmaceuticals, 2022 - mdpi.com
Isatin, chemically an indole-1 H-2, 3-dione, is recognised as one of the most attractive
therapeutic fragments in drug design and development. The template has turned out to be …

Synthesis, spectral characterization, antimicrobial evaluation and molecular docking studies of new Cu (II), Zn (II) thiosemicarbazone based on sulfonyl isatin

A Ezzat, MBI Mohamed, AM Mahmoud… - Journal of Molecular …, 2022 - Elsevier
Abstract Reaction of 5-(morpholinisulfonyl) isatin (1) with thiosemicarbazide derivative
appended the corresponding thiosemicarbazone derivative 3 that further coordinated with …

Michael addition-driven synthesis of cytotoxic palladium (ii) complexes from chromone thiosemicarbazones: investigation of anticancer activity through in vitro and in …

J Haribabu, N Balakrishnan, S Swaminathan… - New Journal of …, 2023 - pubs.rsc.org
Three Pd (II) complexes (1–3) containing tridentate chromone-based thiosemicarbazones
(SVSHL1–3) have been investigated as potential anticancer agents. The complexes of the …

Design and synthesis of heterocyclic azole based bioactive compounds: Molecular structures, quantum simulation, and mechanistic studies through docking as multi …

J Haribabu, V Garisetti, RE Malekshah… - Journal of molecular …, 2022 - Elsevier
Abstract Two heterocyclic azole compounds, 3-(2, 3-dihydrobenzo [d] thiazol-2-yl)-4H-
chromen-4-one (SVS1) and 5-(1H-indol-3-yl)-4-methyl-2, 4-dihydro-3H-1, 2, 4-triazole-3 …

[HTML][HTML] Synthesis, spectral characterization, antimicrobial evaluation studies and cytotoxic activity of some transition metal complexes with tridentate (N, N, O) donor …

HAK Kyhoiesh, KJ Al-Adilee - Results in Chemistry, 2021 - Elsevier
A new azo dye ligand 2-[2'-(6-methoxybenzothiazolyl) azo]-4-ethoxyphenol (6-MBTAEP)
was prepared by reacting a diazonium chloride salt solution of 2-amino-6-methoxy …

Synthesis and characterization of N4-substituted thiosemicarbazones: DNA/BSA binding, molecular docking, anticancer activity, ADME study and computational …

V Manakkadan, J Haribabu… - Journal of Molecular …, 2023 - Elsevier
A series of thiosemicarbazones with the general formula, R− CHdouble bondN− NH− C (S)−
R 1 [R= C 6 H 5 F & R 1= C 4 H 9 NO (TL1), R= C 8 H 10 O 2 & R 1= C 4 H 9 NO (TL2), R= C …

Development of thiosemicarbazone-based transition metal complexes as homogeneous catalysts for various organic transformations

S Priyarega, J Haribabu, R Karvembu - Inorganica Chimica Acta, 2022 - Elsevier
Thiosemicarbazones, an important class of sulphur donor ligands, and their transition metal
complexes are known for their versatile applications in the fields of (bio) catalysis …

Synthesis, crystal structure, Hirshfeld surface analysis, DFT, molecular docking and in vitro antitumor studies of (2E)-2-[4-(diethylamino) benzylidene]-N …

K Preetha, EB Seena, PK Maniyampara… - Journal of Molecular …, 2024 - Elsevier
The crystal structure and spectral characterization of a new proligand,(2E)-2-[4-
(diethylamino) benzylidene]-N-ethylhydrazinecarbothioamide is described. The compound …

Nickel chloride complexes with substituted 4′-phenyl-2′, 2′: 6′, 2 ″-terpyridine ligands: synthesis, characterization, anti-proliferation activity and biomolecule …

B Wang, D Sun, S Wang, M Chen, H Liu, Y Zhou… - JBIC Journal of …, 2023 - Springer
A series of Ni (II) sandwich-like coordinated compounds were synthesized by the reaction of
nickel dichloride and ten 4′-(4-substituent phenyl)-2′, 2′: 6′, 2 ″-terpyridine ligands …