The failure of animal models to predict therapeutic responses in humans is a major problem
that also brings into question their use for basic research. Organ-on-a-chip (organ chip) …

Research in cell biology greatly relies on cell-based in vitro assays and models that facilitate
the investigation and understanding of specific biological events and processes under …

Drug evaluation has always been an important area of research in the pharmaceutical
industry. However, animal welfare protection and other shortcomings of traditional drug …

Membranes play a crucial role in many microfluidic systems, enabling versatile applications
in highly diverse research fields. However, the tight and robust integration of membranes …

Interactions between adipose tissue, liver and immune system are at the center of metabolic
dysfunction-associated steatotic liver disease and type 2 diabetes. To address the need for …

The inefficiency of existing animal models to precisely predict human pharmacological
effects is the root reason for drug development failure. Microphysiological system/organ-on …

Soft tissue defects are a common clinical challenge mostly caused by trauma, congenital
anomalies and oncological surgery. Current soft tissue reconstruction options include …

The advances in cancer immunotherapy come with several obstacles, limiting its
widespread use and benefits so far only to a small subset of patients. One of the underlying …

Over the last decade, Organ-on-Chip (OoC) emerged as a promising technology for
advanced in vitro models, recapitulating key physiological cues. OoC approaches tailored …

Adipose tissue is contemplated as a dynamic organ that plays key roles in the human body.
Adipogenesis is the process by which adipocytes develop from adipose-derived stem cells …