Supported catalysis in continuous‐flow microreactors

R Munirathinam, J Huskens… - Advanced synthesis & …, 2015 - Wiley Online Library
This review surveys the recent developments to perform heterogeneous catalysis in
continuous‐flow microreactors. Three different types, namely,(i) packed‐bed,(ii) monolithic …

Continuous flow synthesis. A pharma perspective

L Malet-Sanz, F Susanne - Journal of medicinal chemistry, 2012 - ACS Publications
The pharmaceutical industry is going through continuous change, and it is only by adapting
to change that it can survive and improve. Enormous pressure to deliver new and successful …

Applying flow chemistry: methods, materials, and multistep synthesis

DT McQuade, PH Seeberger - The Journal of organic chemistry, 2013 - ACS Publications
The synthesis of complex molecules requires control over both chemical reactivity and
reaction conditions. While reactivity drives the majority of chemical discovery, advances in …

Ten key issues in modern flow chemistry

J Wegner, S Ceylan, A Kirschning - Chemical Communications, 2011 - pubs.rsc.org
Ten key issues in modern flow chemistry - Chemical Communications (RSC Publishing) DOI:10.1039/C0CC05060A
Royal Society of Chemistry View PDF VersionPrevious ArticleNext Article DOI: 10.1039/C0CC05060A …

Green asymmetric organocatalysis

D Krištofíková, V Modrocká, M Mečiarová… - …, 2020 - Wiley Online Library
Asymmetric organocatalysis is becoming one of the main tools for the synthesis of chiral
compounds that are needed as medicines, crop protection agents, and other bioactive …

Low-loading asymmetric organocatalysis

F Giacalone, M Gruttadauria, P Agrigento… - Chemical Society …, 2012 - pubs.rsc.org
Asymmetric organocatalysis is now recognized as the third pillar of asymmetric synthesis.
Recent years have witnessed increasing interest towards the use of highly active and …

Asymmetric organocatalysis in continuous flow: opportunities for impacting industrial catalysis

I Atodiresei, C Vila, M Rueping - ACS Catalysis, 2015 - ACS Publications
The review highlights the different advantages associated with organocatalytic
transformations performed in continuous-flow systems and presents the reactions which …

Asymmetric carbon–carbon bond formation under continuous‐flow conditions with chiral heterogeneous catalysts

T Tsubogo, T Ishiwata… - Angewandte Chemie …, 2013 - Wiley Online Library
Catalytic asymmetric carbon–carbon bond‐forming reactions provide one of the most
efficient ways to synthesize optically active compounds, and, accordingly, many chiral …

Inductive heating with magnetic materials inside flow reactors

S Ceylan, L Coutable, J Wegner… - … –A European Journal, 2011 - Wiley Online Library
Superparamagnetic nanoparticles coated with silica gel or alternatively steel beads are new
fixed‐bed materials for flow reactors that efficiently heat reaction mixtures in an inductive …

Reworking organic synthesis for the modern age: Synthetic strategies based on continuous-flow addition and condensation reactions with heterogeneous catalysts

WJ Yoo, H Ishitani, Y Saito, B Laroche… - The Journal of Organic …, 2020 - ACS Publications
While organic synthesis carried out in most laboratories uses batch methods, there is
growing interest in modernizing fine chemical synthesis through continuous-flow processes …