PCR amplification technology is the cornerstone of molecular biology. All-in-One PCR tube,
as an emerging integrated device, is booming in biosensors application. All-in-One PCR …

Translation initiation of the human immunodeficiency virus-type 1 (HIV-1) genomic mRNA
(vRNA) is cap-dependent or mediated by an internal ribosome entry site (IRES). The HIV-1 …

Pathogen sensing via pattern recognition receptors triggers massive reprogramming of
macrophage gene expression. While the signaling cascades and transcription factors that …

BMP6 is an iron‐sensing cytokine whose transcription in liver sinusoidal endothelial cells
(LSECs) is enhanced by high iron levels, a step that precedes the induction of the iron …

The study of proteins is central to unraveling (patho) physiological processes and has
contributed greatly to our understanding of biological systems. Corresponding studies often …

Objective Pancreatic β cell failure plays a central role in the development of type 2 diabetes
(T2D). While the transcription factors shaping the β cell gene expression program have …

Heterogeneous nuclear ribonucleoprotein K (hnRNPK) is an RNA/DNA binding protein
involved in diverse cell processes; it is also a p53 coregulator that initiates apoptosis under …

Genome-wide mechanisms that coordinate expression of subsets of functionally related
genes are largely unknown. Recent studies show that receptor tyrosine kinases and …

Background Disease molecular complexity requires high throughput workflows to map
disease pathways through analysis of vast tissue repositories. Great progress has been …

Pancreatic cyst fluids (PCFs) enriched in tumour‐derived proteins are considered a potential
source of new biomarkers. This study aimed to determine compositional and quantitative …