Transmural myocardial perfusion

JIE Hoffman - Progress in cardiovascular diseases, 1987 - Elsevier
The predilection for subendocardial underperfusion and ischemia is great and must be
considered in the management of any patient, especially if there is coronary artery disease …

Reperfusion in acute myocardial infarction: effect of timing and modulating factors in experimental models

KA Reimer, RS Vander Heide, VJ Richard - The American journal of …, 1993 - Elsevier
Timely reperfusion of ischemic myocardium in experimental animals halts the advancing
transmural “wavefront” of ischemic cell death and thereby limits myocardial infarct size by …

Profound structural alterations of the extracellular collagen matrix in postischemic dysfunctional (“stunned”) but viable myocardium

M Zhao, H Zhang, TF Robinson, SM Factor… - Journal of the American …, 1987 - Elsevier
Ultrastructural studies of the extracellular collagen matrix were made on the “stunned”
myocardium using scanning, conventional and high voltage transmission electron …

Selective inhibition of the contractile apparatus. A new approach to modification of infarct size, infarct composition, and infarct geometry during coronary artery …

D Garcia-Dorado, P Theroux, JM Duran, J Solares… - Circulation, 1992 - Am Heart Assoc
BACKGROUND Myocardial reperfusion is associated with calcium overload and cell
contracture, mechanisms that may precipitate cell death. In this study, we tested the …

Acute ischemia-induced gap junctional uncoupling and arrhythmogenesis

JR De Groot, R Coronel - Cardiovascular research, 2004 - academic.oup.com
Sudden cardiac death forms a major cause of mortality. Myocardial ischemia-induced
ventricular fibrillation (VF) is frequently the underlying mechanism. Ventricular arrhythmias …

Myocardial reperfusion in the pig heart model: infarct size and duration of coronary occlusion

D GARCIA-DORADO, P THÉROUX… - Cardiovascular …, 1987 - academic.oup.com
The effect of coronary artery reperfusion on infarct size was studied in a pig heart model.
Forty four open chest pigs underwent occlusion of the mid-left anterior descending artery …

Connective tissue changes in early ischemia of porcine myocardium: an ultrastructural study

S Sato, M Ashraf, RW Millard, H Fujiwara… - Journal of molecular and …, 1983 - Elsevier
Scanning electron microscopy and transmission electron microscopy were used together
with tannic acid and ruthenium-red staining to examine connective tissue damage caused …

The subendocardial border zone during acute ischemia of the rabbit heart: an electrophysiologic, metabolic, and morphologic correlative study.

RL Wilensky, J Tranum-Jensen, R Coronel, AA Wilde… - Circulation, 1986 - Am Heart Assoc
Isolated preparations of rabbit interventricular septum were perfused through the coronary
arteries with oxygenated Tyrode's solution and placed in a tissue bath where they were …

Determinants of hemorrhagic infarcts. Histologic observations from experiments involving coronary occlusion, coronary reperfusion, and reocclusion.

D Garcia-Dorado, P Theroux, J Solares… - The American journal …, 1990 - ncbi.nlm.nih.gov
Quantification of intramyocardial hemorrhage was performed in 69 pigs submitted to various
protocols of coronary artery occlusion and reperfusion. The study groups include 1) …

Quantitative analysis of contraction band and coagulation necrosis after ischemia and reperfusion in the porcine heart.

S Miyazaki, H Fujiwara, T Onodera, Y Kihara… - Circulation, 1987 - Am Heart Assoc
To assess the importance of contraction band necrosis (CBN) in reperfusion, CBN,
coagulation necrosis (CN), and infarct size, expressed as CBN+ CN, were quantitatively …