Improvements to PATRIC, the all-bacterial bioinformatics database and analysis resource center

AR Wattam, JJ Davis, R Assaf, S Boisvert… - Nucleic acids …, 2017 - academic.oup.com
Abstract The Pathosystems Resource Integration Center (PATRIC) is the bacterial
Bioinformatics Resource Center (https://www. patricbrc. org). Recent changes to PATRIC …

Nextpresso: next generation sequencing expression analysis pipeline

O Graña, M Rubio-Camarillo… - Current …, 2018 - ingentaconnect.com
Background: Many bioinformatics pipelines are available nowadays to analyze
transcriptomics data produced by high-throughput RNA sequencing. They implement …

Cyclic di-GMP modulates gene expression in Lyme disease spirochetes at the tick-mammal interface to promote spirochete survival during the blood meal and tick-to …

MJ Caimano, S Dunham-Ems, AM Allard… - Infection and …, 2015 - Am Soc Microbiol
Borrelia burgdorferi, the Lyme disease spirochete, couples environmental sensing and gene
regulation primarily via the Hk1/Rrp1 two-component system (TCS) and Rrp2/RpoN/RpoS …

Identification of bacterial sRNA regulatory targets using ribosome profiling

J Wang, W Rennie, C Liu, CS Carmack… - Nucleic acids …, 2015 - academic.oup.com
Bacteria express large numbers of non-coding, regulatory RNAs known as 'small
RNAs'(sRNAs). sRNAs typically regulate expression of multiple target messenger RNAs …

De novo assembly and characterization of the Trichuris trichiura adult worm transcriptome using Ion Torrent sequencing

LN Santos, ES Silva, AS Santos, PH De Sá, RT Ramos… - Acta tropica, 2016 - Elsevier
Infection with helminthic parasites, including the soil-transmitted helminth Trichuris trichiura
(human whipworm), has been shown to modulate host immune responses and …

Dynamic changes in the splenic transcriptome of chickens during the early infection and progress of Marek's disease

L Dang, M Teng, HW Li, HZ Li, SM Ma, P Zhao, XJ Li… - Scientific reports, 2017 - nature.com
Abstract Gallid alphaherpesvirus 2 (GaHV2) is an oncogenic avian herpesvirus inducing
Marek's disease (MD) and rapid-onset T-cell lymphomas. To reveal molecular events in MD …

PerC Manipulates Metabolism and Surface Antigens in Enteropathogenic Escherichia coli

JL Mellies, A Platenkamp, J Osborn… - Frontiers in Cellular and …, 2017 - frontiersin.org
Enteropathogenic Escherichia coli is an important cause of profuse, watery diarrhea in
infants living in developing regions of the world. Typical strains of EPEC (tEPEC) possess a …

Transcriptional regulation analysis of Alzheimer's disease based on FastNCA algorithm

Q Sun, W Kong, X Mou, S Wang - Current Bioinformatics, 2019 - ingentaconnect.com
Background: Understanding the relationship between genetic variation and gene
expression is a central issue in genetics. Although many studies have identified genetic …

A transcriptomic approach to identify novel drug efflux pumps in bacteria

L Li, SG Tetu, IT Paulsen, KA Hassan - Bacterial Multidrug Exporters …, 2018 - Springer
The core genomes of most bacterial species include a large number of genes encoding
putative efflux pumps. The functional roles of most of these pumps are unknown, however …

RNA-seq–Revealing Biological Insights in Bacteria

MP Santana, FF Aburjaile, MTD Parise… - Next Generation …, 2016 - books.google.com
New technologies are constantly being released and the improvements therein bring
advances not only to transcriptome, the focus of this chapter, but also to diverse areas of …