The Tet repressor protein (TetR) regulates transcription of a family of tetracycline (tc)
resistance determinants in Gram‐negative bacteria. The resistance protein TetA, a …

▪ Abstract The rapid accumulation of genetic information and advancement of experimental
techniques have opened a new frontier in biomedical engineering. With the availability of …

A key bottleneck in the microbial production of therapeutic plant metabolites is identifying
enzymes that can improve yield. The facile identification of genetically encoded biosensors …

▪ Abstract The prospect of specifically controlling gene activities in vivo has become a
defining hallmark of many model organisms of biological research. Where once the aim was …

Conventional tools for elucidating gene function are relatively scarce in Candida albicans,
the most prevalent human fungal pathogen. To this end, we developed a convenient system …

A promoter‐substitution cassette has been constructed that allows one‐step substitution of
chromosomal gene promoters for the tetracycline‐regulatable tetO promoter in yeast cells …

Recent studies have revealed that fungi possess a mechanism similar to bacterial two-
component systems to respond to extracellular changes in osmolarity. In Saccharomyces …

FKS1 and FKS2 encode alternative catalytic subunits of the glucan synthases that are
responsible for synthesis of β-1, 3-glucan in the Saccharomyces cerevisiae cell wall …

Abstract Background Although Aspergillus fumigatus is an important human fungal
pathogen there are few expression systems available to study the contribution of specific …

We report the construction of a Pichia pastoris integrating vector which contains the
inducible CUP1 promoter from Saccharomyces cerevisiae. We show that the promoter is …