Human respiratory syncytial virus (RSV) is the most important cause of acute lower
respiratory tract disease in infants worldwide. As a first line of defense against respiratory …

Severe respiratory syncytial virus (RSV) infection is a major cause of morbidity and mortality
in infants< 2 years-old. Here we describe that high-fiber diet protects mice from RSV …

Microbiota-derived short-chain fatty acids (SCFAs) are crucial for protecting the intestinal
barrier and regulating the immune response during infections. Recent studies show that viral …

An important property of the host innate immune response during microbial infection is its
ability to control the expression of antimicrobial effector proteins, but how this occurs post …

Interferon-inducible human oligoadenylate synthetase-like (OASL) and its mouse ortholog,
Oasl2, enhance RNA-sensor RIG-I-mediated type I interferon (IFN) induction and inhibit …

Respiratory syncytial virus (RSV) is the leading cause of severe acute lower respiratory tract
infections in infants worldwide. Although several pattern recognition receptors (PRRs) can …

Respiratory syncytial virus (RSV) is the leading cause of severe respiratory infection in
young children. Nearly all individuals become infected in their early childhood, and …

In response to viral infection, how cells balance translational shutdown to limit viral
replication and the induction of antiviral components like interferons (IFNs) is not well …

Influenza A virus (IAV) is a leading cause of human respiratory infections and poses a major
public health concern. IAV replication can affect the expression of DNA methyltransferases …

Host cells develop the OAS/RNase L [2′–5′–oligoadenylate synthetase
(OAS)/ribonuclease L] system to degrade cellular and viral RNA, and/or the OASL/RIG-I (2 …