Metabolic rewiring and epigenetic remodeling, which are closely linked and reciprocally
regulate each other, are among the well-known cancer hallmarks. Recent evidence …

Protein posttranslational modifications (PTMs) refer to the breaking or generation of covalent
bonds on the backbones or amino acid side chains of proteins and expand the diversity of …

Unlocking the potential of protein arginine deiminase 4 (PAD4) as a drug target for
rheumatoid arthritis requires a deeper understanding of its regulation. In this study, we use …

As a systemic autoimmune disease, rheumatoid arthritis (RA) usually causes damage not
only to joints, but also to other tissues and organs including the heart, kidneys, lungs …

The association between rheumatoid arthritis (RA) and periodontal disease (PD) has been
the focus of numerous investigations driven by their common pathological features. RA is an …

When the corona pandemic commenced more than two years ago, it was quickly recognized
that people with metabolic diseases show an augmented risk of severe COVID-19 and an …

Numerous post-translational modifications (PTMs) govern the collective metabolism of a cell
through altering the structure and functions of proteins. The action of the most prevalent …

Rheumatoid arthritis (RA) is a chronic, debilitating autoimmune disorder involving
inflammation and progressive destruction of the joints, affecting up to 1% of the population …

Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint inflammation. In
the last few decades, new insights into RA‐specific autoantibodies and B cells have greatly …

Immunology, already a discipline in its own right, has become a major part of many different
medical fields. However, its relationship to orthopedics and trauma surgery has …