Which cell death modality wins the contest for photodynamic therapy of cancer?

T Mishchenko, I Balalaeva, A Gorokhova… - Cell death & …, 2022 - nature.com
Photodynamic therapy (PDT) was discovered more than 100 years ago. Since then, many
protocols and agents for PDT have been proposed for the treatment of several types of …

Autophagy regulation and photodynamic therapy: Insights to improve outcomes of cancer treatment

WK Martins, R Belotto, MN Silva, D Grasso… - Frontiers in …, 2021 - frontiersin.org
Cancer is considered an age-related disease that, over the next 10 years, will become the
most prevalent health problem worldwide. Although cancer therapy has remarkably …

Recent advances in drug discovery of phototherapeutic non-porphyrinic anticancer agents

M Dichiara, O Prezzavento, A Marrazzo, V Pittala… - European Journal of …, 2017 - Elsevier
In the search of novel strategies for the treatment of cancer, photodynamic therapy (PDT)
has emerged as an effective, safe for repeated use, and non-invasive method. This …

Polypeptide uploaded efficient nanophotosensitizers to overcome photodynamic resistance for enhanced anticancer therapy

Y Li, R Zhou, D Xiao, S Shi, S Peng, S Wu, P Wu… - Chemical Engineering …, 2021 - Elsevier
Being either minimally invasive or non-invasive, photodynamic therapy (PDT) has garnered
much attention in treatment of superficial tumors. However, repeated irradiation of tumors …

Molecular effectors of photodynamic therapy-mediated resistance to cancer cells

EC Aniogo, BP George, H Abrahamse - International journal of molecular …, 2021 - mdpi.com
Photodynamic therapy (PDT) is currently enjoying considerable attention as the subject of
experimental research to treat resistant cancers. The preferential accumulation of a non …

Combating the hypoxia limit of photodynamic therapy through reversing the survival-related pathways of cancer cells

R Zhou, X Zeng, H Zhao, Q Chen, P Wu - Coordination Chemistry Reviews, 2022 - Elsevier
Photodynamic therapy (PDT) is extensively used in the treatment of varied diseases due to
its noninvasive characteristic. However, resistance will also be developed due to tumor …

Development of resistance to photodynamic therapy (PDT) in human breast cancer cells is photosensitizer-dependent: Possible mechanisms and approaches for …

CE Olsen, A Weyergang, VT Edwards, K Berg… - Biochemical …, 2017 - Elsevier
Here we report on the induction of resistance to photodynamic therapy (PDT) in the ABCG2-
high human breast cancer cell line MA11 after repetitive PDT, using either Pheophorbide A …

[HTML][HTML] Increased DNA repair capacity augments resistance of glioblastoma cells to photodynamic therapy

SS Ghahe, K Kosicki, M Wojewódzka, BA Majchrzak… - DNA repair, 2021 - Elsevier
Photodynamic therapy (PDT) is a clinically approved cancer therapy of low invasiveness.
The therapeutic procedure involves administering a photosensitizing drug (PS), which is …

Resistance of oral cancer cells to 5‐ALA‐mediated photodynamic therapy

FCP Rosin, MG Teixeira, C Pelissari… - Journal of Cellular …, 2018 - Wiley Online Library
Photodynamic therapy (PDT) has been indicated for oral squamous cell carcinoma (OSCC)
at early stages. Chemo and radio‐resistance are frequently observed in OSCC, but it is …

[HTML][HTML] Significant difference in response of malignant tumor cells of individual patients to photodynamic treatment as revealed by digital holographic microscopy

AA Zhikhoreva, AV Belashov, AB Danilova… - … of Photochemistry and …, 2021 - Elsevier
The investigation of in-vitro response of cell cultures derived from tumor material of
individual patients with similar tumor localizations to photodynamic treatment is presented …