Multiacting receptor-targeting antipsychotics and tricyclic antidepressants stimulate various
neurotransmitter receptors despite the different targets of postsynaptic receptors and …

Wells introduced nitrous oxide for pain relief during dental surgery, and William TG Morton
gave the first public demonstration of ether anesthesia and spread the word about its …

Background: Endotracheal intubation is of paramount importance in general anaesthesia
requires relaxation of laryngeal musculature leading to total inactivity of vocal cords …

Following his November 1841 Manchester encounter with Charles Lafontaine, and due to
the mesmerism-induced'somnolence'that Lafontaine had demonstrated, and the sporadic …

Throughout history, accounts detailing innovative medical treatments for individual patients
have served as a driver of medical advancements. 1 More than 4000 years ago, the …

The introduction of anaesthesia on 16 October 1846 brought about tremendous changes in
the discipline of surgery. We sought to determine whether the concept of painless surgery …

Understanding the signs of laboratory animal distress, pain and anxiety and its mitigation is
quintessential in obtaining meaningful results from animal studies. Even routine …

Serendipia, una palabra común en la literatura científica en inglés; pero que luego de casi
300 años de su acuñación no ha sido aceptada por la Real Academia Española. En todo …

History of medicine does not receive the coverage it deserves in medical school curricula, or
during graduate medical training, in part, because of its lack of impact on direct clinical care …

Nos dias de hoje, em pleno século XXI, seria impensável submeter-nos a um procedimento
mais invasivo sem antes nos assegurarmos, através do uso de anestésicos, que o mesmo …