Emerging Near-Infrared Targeting Diagnostic and Therapeutic Strategies for Ischemic Cardiovascular and Cerebrovascular Diseases

M Yu, H Wu, H Hu, Y Cheng, Y Qin, K Yang, CH Hu… - Acta Biomaterialia, 2024 - Elsevier
Ischemic cardiovascular and cerebrovascular diseases (ICCDs), including thrombosis,
ischemic stroke and atherosclerosis, represent a significant threat to human health, and …

Advances in nanomaterial-targeted treatment of acute lung injury after burns

S Zhang, X Zhao, Y Xue, X Wang, XL Chen - Journal of …, 2024 - Springer
Acute lung injury (ALI) is a common complication in patients with severe burns and has a
complex pathogenesis and high morbidity and mortality rates. A variety of drugs have been …

Spermatozoon-propelled microcellular submarines combining innate magnetic hyperthermia with derived nanotherapies for thrombolysis and ischemia mitigation

PW Weng, CH Liu, PR Jheng, CC Chiang… - Journal of …, 2024 - Springer
Thrombotic cardiovascular diseases are a prevalent factor contributing to both physical
impairment and mortality. Thrombolysis and ischemic mitigation have emerged as leading …

Alleviating rheumatoid arthritis with a photo-pharmacotherapeutic glycan-integrated nanogel complex for advanced percutaneous delivery

PW Weng, HT Lu, L Rethi, CH Liu, CC Wong… - Journal of …, 2024 - Springer
The prospective of percutaneous drug delivery (PDD) mechanisms to address the limitations
of oral and injectable treatment for rheumatoid arthritis (RA) is increasing. These limitations …

Nasal administration of polysaccharides-based nanocarrier combining hemoglobin and diferuloylmethane for managing diabetic kidney disease

AEY Chuang, YL Chen, HJ Chiu, HT Nguyen… - International Journal of …, 2024 - Elsevier
The management of diabetic kidney disease (DKD) faces challenges stemming from
intricate pathologies and suboptimal biodistributions during drug delivery. Although clinically …

Long-circulating nanoparticles as passive targeting nanocarriers for the treatment of thrombosis

J Li, K Lu, S Sun, J Peng, L Zhao - Nanoscale, 2024 - pubs.rsc.org
Thrombosis is the major cause of cardiovascular diseases. Only a small subset of patients
could benefit from thrombolytic therapy due to the high bleeding risk brought about by the …

Phototactic/Photosynthetic/Magnetic‐Powered Chlamydomonas Reinhardtii‐Metal‐Organic Frameworks Micro/Nanomotors for Intelligent Thrombolytic Management …

CC Chiang, CH Liu, L Rethi, HT Nguyen… - Advanced …, 2024 - Wiley Online Library
Thrombosis presents a critical health threat globally, with high mortality and incidence rates.
Clinical treatment faces challenges such as low thrombolytic agent bioavailability …

A microthrombus-driven fixed-point cleaved nanosystem for preventing post-thrombolysis recurrence via inhibiting ferroptosis

M Sun, C Liu, J Liu, J Wen, T Hao, D Chen… - Journal of Controlled …, 2024 - Elsevier
Thrombus-induced cardiovascular diseases threaten human health. Current treatment
strategies often rely on urokinase plasminogen activator (uPA) for its efficacy, yet it has such …

[HTML][HTML] Cold atmospheric plasma-enabled platelet vesicle incorporated iron oxide nano-propellers for thrombolysis

PR Jheng, CC Chiang, JH Kang, YJ Fan, KCW Wu… - Materials Today Bio, 2023 - Elsevier
A new approach to treating vascular blockages has been developed to overcome the
limitations of current thrombolytic therapies. This approach involves biosafety and …

Biological Photonic Devices Designed for the Purpose of Bio-Imaging with Bio-Diagnosis

SC Chuang, SA Yu, PC Hung, HT Lu, HT Nguyen… - Photonics, 2023 - mdpi.com
The rapid progress in the fields of biomedical and biological photonic sciences has given
rise to a substantial demand for biological photonic structures capable of interacting with …