Recent advances in the treatment of insulin resistance targeting molecular and metabolic pathways: fighting a losing battle?

M Wolosowicz, S Prokopiuk, TW Kaminski - Medicina, 2022 - mdpi.com
Diabetes Mellitus (DM) is amongst the most notable causes of years of life lost worldwide
and its prevalence increases perpetually. The disease is characterized as multisystemic …

Incretins as a potential treatment option for gestational diabetes mellitus

A Pilszyk, M Niebrzydowska, Z Pilszyk… - International Journal of …, 2022 - mdpi.com
Gestational diabetes mellitus (GDM) is a metabolic disease affecting an increasing number
of pregnant women around the world. It is not only associated with numerous perinatal …

Vitamin D supplementation improves mitochondrial function and reduces inflammation in placentae of obese women

EA Phillips, N Hendricks, M Bucher… - Frontiers in …, 2022 - frontiersin.org
Background About 30% of women entering pregnancy in the US are obese. We have
previously reported mitochondrial dysregulation and increased inflammation in the …

Metabolic abnormalities in the bone marrow cells of young offspring born to mothers with obesity

EA Phillips, YJ Alharithi, L Kadam… - International Journal of …, 2024 - nature.com
Abstract Background/Objectives Intrauterine metabolic reprogramming occurs in mothers
with obesity during gestation, putting the offspring at high risk of developing obesity and …

[HTML][HTML] Maternal high-fat diet increases airway sensory innervation and reflex bronchoconstriction in adult offspring

GN Calco, YJ Alharithi, KR Williams… - … of Physiology-Lung …, 2023 - journals.physiology.org
Children born to obese mothers are prone to develop asthma and airway
hyperresponsiveness, but the mechanisms behind this are unclear. Here we developed a …

Association of dpp-4 concentrations with the occurrence of gestational diabetes mellitus and excessive gestational weight gain

M Niebrzydowska-Tatus, A Pełech, K Bień… - International Journal of …, 2024 - mdpi.com
Gestational diabetes mellitus (GDM) is considered one of the most common diseases that
occur during pregnancy. In addition to increasing the risk of numerous complications …

Gut-derived peptide hormone receptor expression in the developing mouse hypothalamus

L Cantacorps, BM Coull, J Falck, K Ritter, RN Lippert - PLoS One, 2023 - journals.plos.org
Objective In adult organisms, a number of receptors have been identified which modulate
metabolic processes related to peptides derived from the intestinal tract. These receptors …

Metabolomic and transcriptomic remodeling of bone marrow myeloid cells in response to maternal obesity

YJ Alharithi, EA Phillips, TD Wilson… - American Journal …, 2024 - journals.physiology.org
Maternal obesity puts the offspring at high risk of developing obesity and cardio-metabolic
diseases in adulthood. Here, we utilized a mouse model of maternal high-fat diet (HFD) …

Metabolic abnormalities in the bone marrow cells of young offspring born to obese mothers

E Phillips, Y Alharithi, L Kadam, LM Coussens… - bioRxiv, 2023 - biorxiv.org
Intrauterine metabolic reprogramming occurs in obese mothers during gestation, putting the
offspring at high risk of developing obesity and associated metabolic disorders even before …

[HTML][HTML] Metabolic abnormalities in the bone marrow cells of young offspring born to obese mothers

M Alina, E Phillips, Y Alharithi, L Kadam… - Research …, 2024 - ncbi.nlm.nih.gov
Intrauterine metabolic reprogramming occurs in obese mothers during gestation, putting the
offspring at high risk of developing obesity and associated metabolic disorders even before …