Altered gene expression is the primary molecular mechanism responsible for the
pathological processes of human diseases, including cancer. MicroRNAs (miRNAs) are …

Thousands of unique non-coding RNA (ncRNA) sequences exist within cells. Work from the
past decade has altered our perception of ncRNAs from'junk'transcriptional products to …

MYC oncogene is a transcription factor with a wide array of functions affecting cellular
activities such as cell cycle, apoptosis, DNA damage response, and hematopoiesis. Due to …

MicroRNAs are small noncoding transcripts that posttranscriptionally regulate gene
expression via base-pairing complementarity. Their role in cancer can be related to tumor …

MicroRNAs (miRNAs) are endogenous, small non‐coding RNAs known to regulate
expression of protein‐coding genes. A large proportion of miRNAs are highly conserved …

Cancer has become the second greatest cause of death worldwide. Although there are
several different classes of anticancer drugs that are available in clinic, some tough issues …

In addition to the deregulation of gene transcriptions and post-translational protein
modifications, the aberrant translation from mRNAs to proteins plays an important role in the …

Acyl-CoA synthetase long-chain family member 4 (ACSL4) is an important isozyme in
polyunsaturated fatty acid (PUFA) metabolism. The role of ACSL4 in the lipopolysaccharide …

High-grade B-cell lymphomas with MYC and BCL2 and/or BCL6 rearrangements (HGBL-
DH/THs) include a group of diffuse large B-cell lymphomas (DLBCLs) with inferior outcomes …

Imbalanced regulation of reactive oxygen species (ROS) and antioxidant factors in cells is
known as “oxidative stress (OS)”. OS regulates key cellular physiological responses through …