Hormonal regulation of mammary gland development and lactation

FM Hannan, T Elajnaf, LN Vandenberg… - Nature Reviews …, 2023 - nature.com
Lactation is critical to infant short-term and long-term health and protects mothers from
breast cancer, ovarian cancer and type 2 diabetes mellitus. The mammary gland is a …

[HTML][HTML] Networks behind the morphology and structural design of living systems

M Gosak, M Milojević, M Duh, K Skok, M Perc - Physics of Life Reviews, 2022 - Elsevier
Technological advances in imaging techniques and biometric data acquisition have enabled
us to apply methods of network science to study the morphology and structural design of …

Estrogen receptor-α signaling in post-natal mammary development and breast cancers

M Rusidzé, M Adlanmérini, E Chantalat… - Cellular and Molecular …, 2021 - Springer
Abstract 17β-estradiol controls post-natal mammary gland development and exerts its effects
through Estrogen Receptor ERα, a member of the nuclear receptor family. ERα is also …

From isles of Königsberg to islets of Langerhans: examining the function of the endocrine pancreas through network science

A Stožer, M Šterk, E Paradiž Leitgeb… - Frontiers in …, 2022 - frontiersin.org
Islets of Langerhans are multicellular microorgans located in the pancreas that play a central
role in whole-body energy homeostasis. Through secretion of insulin and other hormones …

[HTML][HTML] Human cancer cells generate spontaneous calcium transients and intercellular waves that modulate tumor growth

C Liang, Q Zhang, X Chen, J Liu, M Tanaka, S Wang… - Biomaterials, 2022 - Elsevier
Electrically excitable cells such as neurons transmit long-distance calcium or electrical
signals to regulate their physiological functions. While the molecular underpinnings and …

[HTML][HTML] Zebrafish (Danio rerio) as a translational model for neuro-immune interactions in the enteric nervous system in autism spectrum disorders

AIS Andersen-Civil, RA Sawale… - Brain, Behavior, and …, 2023 - Elsevier
Autism spectrum disorders (ASD) affect about 1% of the population and are strongly
associated with gastrointestinal diseases creating shortcomings in quality of life. Multiple …

Gene expression signatures of individual ductal carcinoma in situ lesions identify processes and biomarkers associated with progression towards invasive ductal …

CA Rebbeck, J Xian, S Bornelöv, J Geradts… - Nature …, 2022 - nature.com
Ductal carcinoma in situ (DCIS) is considered a non-invasive precursor to breast cancer,
and although associated with an increased risk of developing invasive disease, many …

Developmental stage-specific distribution of macrophages in mouse mammary gland

TA Stewart, K Hughes, DA Hume… - Frontiers in Cell and …, 2019 - frontiersin.org
Mammary gland development begins in the embryo and continues throughout the
reproductive life of female mammals. Tissue macrophages (Mϕs), dependent on signals …

Calcium imaging and the curse of negativity

G Vanwalleghem, L Constantin, EK Scott - Frontiers in neural circuits, 2021 - frontiersin.org
The imaging of neuronal activity using calcium indicators has become a staple of modern
neuroscience. However, without ground truths, there is a real risk of missing a significant …

Animal models for in vivo lactation studies: anatomy, physiology and milk compositions in the most used non-clinical species: a contribution from the ConcePTION …

D Ventrella, N Ashkenazi, A Elmi, K Allegaert… - Animals, 2021 - mdpi.com
Simple Summary Nowadays, the importance of breastfeeding has been very well
recognized not only by the scientific world but also by public opinion. Such awareness has …