Molecular technologies, including high-throughput sequencing, have expanded our
perception of the microbial world. Unprecedented insights into the composition and function …

Recurrent urinary tract infections (rUTIs) are a major health burden worldwide, with history of
infection being a significant risk factor. While the gut is a known reservoir for uropathogenic …

Advancements in next-generation sequencing technology have dramatically reduced the
cost and increased the ease of microbial whole genome sequencing. This approach is …

Multidrug-resistant organism (MDRO) colonization is a fundamental challenge in
antimicrobial resistance. Limited studies have shown that fecal microbiota transplantation …

Although compositional variation in the gut microbiome during human development has
been extensively investigated, strain-resolved dynamic changes remain to be fully …

Opportunistic bacterial pathogen species and their strains that colonise the human gut are
generally understood to compete against both each other and the commensal species …

Background Culture-based studies have shown that acquisition of extended-spectrum β-
lactamase-producing Enterobacterales is common during international travel; however, little …

Background Bacterial strains under the same species can exhibit different biological
properties, making strain-level composition analysis an important step in understanding the …

Klebsiella pneumoniae is an important opportunistic healthcare-associated pathogen and
major contributor to the global spread of antimicrobial resistance. Gastrointestinal …

Background Gestational age (GA) and associated level of gastrointestinal tract maturation
are major factors driving the initial gut microbiota composition in preterm infants. Besides …