Vasculogenic mimicry in carcinogenesis and clinical applications

Q Luo, J Wang, W Zhao, Z Peng, X Liu, B Li… - Journal of hematology & …, 2020 - Springer
Distinct from classical tumor angiogenesis, vasculogenic mimicry (VM) provides a blood
supply for tumor cells independent of endothelial cells. VM has two distinct types, namely …

Vasculogenic mimicry, a complex and devious process favoring tumorigenesis–interest in making it a therapeutic target

L Treps, S Faure, N Clere - Pharmacology & therapeutics, 2021 - Elsevier
Tumor cell vasculogenic mimicry (VM), also dubbed vascular mimicry, describes the
plasticity of aggressive cancer cells forming de novo vascular networks and is associated …

Vasculogenic mimicry in breast cancer: clinical relevance and drivers

G Morales-Guadarrama, R García-Becerra… - Cells, 2021 - mdpi.com
In solid tumors, vasculogenic mimicry (VM) is the formation of vascular structures by cancer
cells, allowing to generate a channel-network able to transport blood and tumor cells. While …

An overview of vasculogenic mimicry in breast cancer

MA Andonegui-Elguera, Y Alfaro-Mora… - Frontiers in …, 2020 - frontiersin.org
Vasculogenic mimicry (VM) is the formation of vascular channels lacking endothelial cells.
These channels are lined by tumor cells with cancer stem cell features, positive for periodic …

Mesenchymal stem cell-derived exosomes as new tools for delivery of miRNAs in the treatment of cancer

A Dalmizrak, O Dalmizrak - Frontiers in Bioengineering and …, 2022 - frontiersin.org
Although ongoing medical research is working to find a cure for a variety of cancers, it
continues to be one of the major causes of death worldwide. Chemotherapy and …

[HTML][HTML] Molecular mechanisms and anticancer therapeutic strategies in vasculogenic mimicry

X Zhang, J Zhang, H Zhou, G Fan, Q Li - Journal of Cancer, 2019 - ncbi.nlm.nih.gov
Vasculogenic mimicry (VM) is a vascular formation mechanism used by aggressive tumor
cells. VM provides an alternative pathway for adequate blood perfusion and challenges the …

Mechanisms of vasculogenic mimicry in ovarian cancer

L Ayala-Domínguez, L Olmedo-Nieva… - Frontiers in …, 2019 - frontiersin.org
Solid tumors carry out the formation of new vessels providing blood supply for growth, tumor
maintenance, and metastasis. Several processes take place during tumor vascularization. In …

MicroRNAs: important players in breast cancer angiogenesis and therapeutic targets

BM Hussen, ST Abdullah, MF Rasul, A Salihi… - Frontiers in molecular …, 2021 - frontiersin.org
The high incidence of breast cancer (BC) is linked to metastasis, facilitated by tumor
angiogenesis. MicroRNAs (miRNAs or miRs) are small non-coding RNA molecules that …

Hypoxia promotes vasculogenic mimicry formation by vascular endothelial growth factor A mediating epithelial‐mesenchymal transition in salivary adenoid cystic …

H Wang, S Wang, M Zheng, L Dai, K Wang… - Cell …, 2019 - Wiley Online Library
Objectives To investigate the role of hypoxia in vasculogenic mimicry (VM) of salivary
adenoid cystic carcinoma (SACC) and the underlying mechanism involved. Materials and …

[HTML][HTML] AngiomiRs: MicroRNAs driving angiogenesis in cancer

YM Salinas‑Vera, LA Marchat… - International …, 2019 - spandidos-publications.com
Angiogenesis is an important hallmark of cancer serving a key role in tumor growth and
metastasis. Therefore, tumor angiogenesis has become an attractive target for development …