Myosin isoforms, muscle fiber types, and transitions

D Pette, RS Staron - Microscopy research and technique, 2000 - Wiley Online Library
Skeletal muscle is an extremely heterogeneous tissue composed of a variety of fast and
slow fiber types and subtypes. Moreover, muscle fibers are versatile entities capable of …

Mammalian skeletal muscle fiber type transitions

D Pette, RS Staron - International review of cytology, 1997 - Elsevier
abstract Mammalian skeletal muscle is an extremely heterogeneous tissue, composed of a
large variety of fiber types. These fibers, however, are not fixed units but represent highly …

Transitions of muscle fiber phenotypic profiles

D Pette, RS Staron - Histochemistry and cell biology, 2001 - Springer
Skeletal muscle is a complex, versatile tissue composed of a large variety of functionally
diverse fiber types. The overall properties of a muscle largely result from a combination of …

Cardiac and skeletal muscle adaptations to voluntary wheel running in the mouse

DL Allen, BC Harrison, A Maass… - Journal of applied …, 2001 - journals.physiology.org
In this paper, we describe the effects of voluntary cage wheel exercise on mouse cardiac
and skeletal muscle. Inbred male C57/Bl6 mice (age 8–10 wk; n= 12) ran an average of 4.3 …

Myosin heavy chain isoforms in postnatal muscle development of mice

O Agbulut, P Noirez, F Beaumont, G Butler-Browne - Biology of the Cell, 2003 - Elsevier
In this study, using a high-resolution gel electrophoresis technique, we have characterized
the myosin heavy chain composition in different skeletal muscle of the mouse during …

Evolving concepts on the age-related changes in “muscle quality”

DW Russ, K Gregg-Cornell, MJ Conaway… - Journal of cachexia …, 2012 - Springer
The deterioration of skeletal muscle with advancing age has long been anecdotally
recognized and has been of scientific interest for more than 150 years. Over the past several …

Specific force deficit in skeletal muscles of old rats is partially explained by the existence of denervated muscle fibers

MG Urbanchek, EB Picken, LK Kalliainen… - The Journals of …, 2001 - academic.oup.com
We tested the hypothesis that denervated muscle fibers account for part of the specific force
(sF o) deficit observed in muscles from old adult (OA) mammals. Whole muscle force (F o) …

Clinical-grade human umbilical cord-derived mesenchymal stem cells improved skeletal muscle dysfunction in age-associated sarcopenia mice

C Wang, B Zhao, J Zhai, A Wang, N Cao, T Liao… - Cell Death & …, 2023 - nature.com
With the expansion of the aging population, age-associated sarcopenia (AAS) has become
a severe clinical disease of the elderly and a key challenge for healthy aging. Regrettably …

The mitochondrial multi-omic response to exercise training across rat tissues

D Amar, NR Gay, D Jimenez-Morales, PMJ Beltran… - Cell Metabolism, 2024 - cell.com
Mitochondria have diverse functions critical to whole-body metabolic homeostasis.
Endurance training alters mitochondrial activity, but systematic characterization of these …

Muscle aging and sarcopenia: The pathology, etiology, and most promising therapeutic targets

M Grima-Terrén, S Campanario… - Molecular Aspects of …, 2024 - Elsevier
Sarcopenia is a progressive muscle wasting disorder that severely impacts the quality of life
of elderly individuals. Although the natural aging process primarily causes sarcopenia, it can …