Single-molecule optical genome mapping in nanochannels: multidisciplinarity at the nanoscale

J Jeffet, S Margalit, Y Michaeli… - Essays in …, 2021 - portlandpress.com
The human genome contains multiple layers of information that extend beyond the genetic
sequence. In fact, identical genetics do not necessarily yield identical phenotypes as evident …

DNA Programmable Peroxidase Activity of Oxidized Polypyrrole Quantum Dots

W Yang, T Leng, H Sun, W Miao… - Advanced Functional …, 2023 - Wiley Online Library
Significant progress has recently been made in the application of oxidized graphene (GO)
quantum dots as enzyme mimics in various biomedical fields due to their bio‐compatibility …

Dam assisted fluorescent tagging of chromatin accessibility (dafca) for optical genome mapping in nanochannel arrays

G Nifker, A Grunwald, S Margalit, Z Tulpova… - ACS …, 2023 - ACS Publications
Proteins and enzymes in the cell nucleus require physical access to their DNA target sites in
order to perform genomic tasks such as gene activation and transcription. Hence, chromatin …

Sensing base modifications in non-canonically folded DNA with an optimized host: Guest sensing array

J Chen, BL Hickey, Z Gao, AAP Raz, RJ Hooley… - ACS …, 2022 - ACS Publications
An arrayed host: guest fluorescence sensor system can discriminate DNA G-quadruplex
structures that differ only in the presence of single oxidation or methylation modification in …

Electrochemical DNA Biosensors Based on the Intrinsic Topological Insulator BiSbTeSe2 for Potential Application in HIV Determination

Y Jiang, S Li, P Zhu, J Zhao, X Xiong, Y Wu… - ACS Applied Bio …, 2022 - ACS Publications
In this work, we reported a sensitive, label-free electrochemical biosensor based on the
intrinsic topological insulator (TI) BiSbTeSe2 for potential application in the determination of …

Plasmonics: An Optical Approach to Study Plant Epigenetics

MB Mamián-López, K Begcy - Plasmonics, 2024 - Springer
Essential factors that control gene stability and expression are collectively known as
epigenetics. Within the most well-studied epigenetic mechanisms are DNA methylation and …

Global modulation in DNA epigenetics during pro-inflammatory macrophage activation

N Jain, T Shahal, T Gabrieli, N Gilat, D Torchinsky… - Epigenetics, 2019 - Taylor & Francis
ABSTRACT DNA methylation patterns create distinct gene-expression profiles. These
patterns are maintained after cell division, thus enabling the differentiation and maintenance …

Hydrogen bonding and protonation effects in amino acids' anthraquinone derivatives-Spectroscopic and electrochemical studies

S Ramotowska, D Zarzeczańska, I Dąbkowska… - … Acta Part A: Molecular …, 2019 - Elsevier
Six novel amino acid chromophores were synthesized and their spectroscopic, acid-base,
and electrochemical properties are discussed in this work. In studied compounds, selected …

Label as you fold: methyltransferase-assisted functionalization of DNA nanostructures

C Heck, D Torchinsky, G Nifker, F Gularek, Y Michaeli… - Nanoscale, 2020 - pubs.rsc.org
Non-DNA labels are key components for the construction of functional DNA nanostructures.
Here, we present a method to graft covalent labels onto DNA origami nanostructures in an …

Photoelectrochemical Biosensor for 5‐Formylcytosine Based on WS2/Bi/Bi2O2CO3 Nanocomposite and Rolling Circle Amplification

Q Wang, H Yin, Y Zhou, L Cao, Z Yu… - Chinese Journal of …, 2022 - Wiley Online Library
Comprehensive Summary As a key epigenetic modification, 5‐formylcytosine (5fC) controls
many important cell functions, such as gene expression and cell differentiation. However …