Methyl group metabolism in differentiation, aging, and cancer

L Erichsen, C Thimm, S Santourlidis - International journal of molecular …, 2022 - mdpi.com
Methyl group metabolism belongs to a relatively understudied field of research. Its
importance lies in the fact that methyl group metabolic pathways are crucial for the …

Evaluation of the MTHFR C677T polymorphism as a risk factor for colorectal cancer in Asian populations

V Rai - Asian Pacific Journal of Cancer Prevention, 2016 - journal.waocp.org
Background: Genetic and environmental factors play important roles in pathogenesis of
digestive tract cancers like those in the esophagus, stomach and colorectum. Folate …

Methylenetetrahydrofolate reductase C677T polymorphism and colorectal cancer susceptibility: a meta-analysis

L Xu, Z Qin, F Wang, S Si, L Li, P Lin, X Han… - Bioscience …, 2017 - portlandpress.com
The association between methylenetetrahydrofolate reductase (MTHFR) C677T
polymorphism and colorectal cancer (CRC) susceptibility has been researched in numerous …

Relationship between genetic polymorphisms in MTHFR (C677T, A1298C and their haplotypes) and the incidence of breast cancer among Jordanian females-case …

N Awwad, AM Yousef, A Abuhaliema… - Asian Pacific Journal …, 2015 - koreascience.kr
Background: Breast cancer is a major cause of morbidity and mortality in Jordan and
worldwide. Abnormality of DNA methylation is a possible mechanism for the development of …

Association of single nucleotide polymorphisms of ERCC1 and XPF with colorectal cancer risk and interaction with tobacco use

R Hou, Y Liu, YE Feng, L Sun, Z Shu, J Zhao, S Yang - Gene, 2014 - Elsevier
We investigated the association between polymorphisms in excision repair cross-
complementation group 1 (ERCC1)(rs3212986, rs2298881 and rs11615) and xeroderma …

Combined effect of polymorphisms of MTHFR and MTR and arsenic methylation capacity on developmental delay in preschool children in Taiwan

YM Hsueh, YC Lin, CJ Chung, YL Huang, RL Hsieh… - Archives of …, 2020 - Springer
Polymorphisms of methylenetetrahydrofolate reductase (MTHFR) and methionine synthase
(MTR) are related to cognitive dysfunction and mental disability. These genes, along with …

Methylenetetrahydrofolate reductase gene germ-line C677T and A1298C SNPs are associated with colorectal cancer risk in the Turkish population

F ÖZEN, M ŞEN, Ö ÖZDEMİR - Asian Pacific Journal of …, 2014 - avesis.cumhuriyet.edu.tr
Colorectal cancer (CRC) is the third most common cause of death due to cancer in the
worldwide and the incidence is also increasing in Turkey. Our present aim was to investigate …

Analysis of genetic polymorphism of methylenetetrahydrofolate reductase in a large ethnic Hakka population in southern China

P Zhao, J Hou, H Wu, M Zhong - Medicine, 2018 - journals.lww.com
Methylenetetrahydrofolate reductase (MTHFR) catalyzes conversion of methylene
tetrahydrofolate to methylte trahydrofolate. MTHFR C677T polymorphism has been regarded …

KASP-PCR method to screen thrombophilia genetic risk factors

R Altwayan, H Tombuloglu, A Alhusil, T Awadh… - medRxiv, 2023 - medrxiv.org
Thrombophilia is defined as the willingness of blood to clot easily in a situation of
imbalances between fibrinolysis and coagulation. It is classified as inherited and acquired …

[HTML][HTML] The protective effects of the methylenetetrahydrofolate reductase rs1801131 variant among Saudi smokers

MH Almutairi, NS Al-Numair, NR Parine… - Saudi Journal of …, 2021 - Elsevier
Methylenetetrahydrofolate reductase (MTHFR) polymorphism plays a fundamental role in
susceptibility to various diseases, including cancers and autoimmune diseases. In the …