Synthesis, reactions and application of chalcones: A systematic review
Chalcones are a group of naturally occurring compounds that have biological effects that
include anti-inflammatory, anti-cancer, and antibacterial properties. Current chalcone …
include anti-inflammatory, anti-cancer, and antibacterial properties. Current chalcone …
Hydroxy chalcones and analogs with chemopreventive properties
The aim of this review is to highlight the chemopreventive properties of hydroxy-substituted
natural and synthetic chalcones along with a number of their analogs. These products …
natural and synthetic chalcones along with a number of their analogs. These products …
Exploring α, β-unsaturated carbonyl compounds against bacterial efflux pumps via computational approach
S Dey, S Rathod, K Gumphalwad, N Yadav… - Journal of …, 2024 - Taylor & Francis
Antibiotic resistance has become a pressing global health crisis, with bacterial infections
increasingly difficult to treat due to the emergence of multidrug resistance. This study aims to …
increasingly difficult to treat due to the emergence of multidrug resistance. This study aims to …
Chalcones reloaded: an integration of network pharmacology and molecular docking for type 2 diabetes therapy
S Sabarathinam, N Ganamurali - Journal of Biomolecular Structure …, 2024 - Taylor & Francis
Chalcones have various biological effects, from immune boosting to anti-cancer and anti-
diabetic. Structurally modified chalcones (SMC) are clinically relevant for diabetes and …
diabetic. Structurally modified chalcones (SMC) are clinically relevant for diabetes and …
Promising Antimycobacterial Activities of Flavonoids against Mycobacterium sp. Drug Targets: A Comprehensive Review
AA Rabaan, S Alhumaid, H Albayat, M Alsaeed… - Molecules, 2022 - mdpi.com
Tuberculosis (TB) caused by the bacterial pathogen Mycobacterium tuberculosis (Mtb)
remains a threat to mankind, with over a billion of deaths in the last two centuries. Recent …
remains a threat to mankind, with over a billion of deaths in the last two centuries. Recent …
Synthesis, Structure, and Biologic Activity of Some Copper, Nickel, Cobalt, and Zinc Complexes with 2‐Formylpyridine N4‐Allylthiosemicarbazone
A series of zinc (II)([Zn (H2O)(L) Cl](1)), copper (II)([Cu (L) Cl](2),[Cu (L) Br](3),[Cu2 (L) 2
(CH3COO) 2]· 4H2O (4)), nickel (II)([Ni (HL) 2] Cl2· H2O (5)), and cobalt (III)([Co (L) 2] Cl (6)) …
(CH3COO) 2]· 4H2O (4)), nickel (II)([Ni (HL) 2] Cl2· H2O (5)), and cobalt (III)([Co (L) 2] Cl (6)) …
Synthesis and In Vitro Studies for Structure-Based Design of Novel Chalcones As Antitubercular Agents Targeting InhA
Background: The authors aimed to estimate the therapeutic potential of novel chalcones
against tuberculosis. Methods: 11 synthesized compounds were tested for in vitro …
against tuberculosis. Methods: 11 synthesized compounds were tested for in vitro …
Transition Metal‐Catalyzed Transformations of Chalcones
CMM Santos, AMS Silva - The Chemical Record, 2024 - Wiley Online Library
Chalcones are a class of naturally occurring flavonoid compounds associated to a variety of
biological and pharmacological properties. Several reviews have been published describing …
biological and pharmacological properties. Several reviews have been published describing …
The significance of persisters in tuberculosis drug discovery: Exploring the potential of targeting the glyoxylate shunt pathway
The significant challenge in confronting TB eradication is the discursive treatment that
results in the disease reactivation, patient non compliance and drug resistance. The …
results in the disease reactivation, patient non compliance and drug resistance. The …
Chalcones as anti-infective agents for effective management of tuberculosis
S Mishra, P Jana - Polycyclic Aromatic Compounds, 2024 - Taylor & Francis
After the pandemic COVID-19, global health agencies remind us that tuberculosis is the
deadliest infectious disease worldwide. As per WHO reports, approximately ten million …
deadliest infectious disease worldwide. As per WHO reports, approximately ten million …