Neurodegenerative diseases are caused by the progressive loss of function or structure of
nerve cells in the central nervous system. The most common neurodegenerative diseases …

The appropriate regulation of intracellular calcium is a requirement for proper cell function
and survival. This review focuses on the effects of proinflammatory cytokines on calcium …

Oxidative stress and Ca2+ toxicity are mechanisms of hypoxic–ischemic (HI) brain injury.
This work investigates if partial inhibition of mitochondrial respiratory chain protects HI brain …

The present work demonstrates the ability of CO to prevent apoptosis in a primary culture of
astrocytes. For the first time, the antiapoptotic behavior can be clearly attributed to the …

The significance of reactive oxygen species (ROS) as aggravating or primary factors in
numerous pathologies is widely recognized, with mitochondria being considered the major …

Objective: We have previously identified peroxiredoxin-3 (PRDX-3) as a cell-surface protein
that is androgen regulated in the LNCaP prostate cancer (PCa) cell line. PRDX-3 is a …

The ABCC9 gene and its polypeptide product, SUR2, are increasingly implicated in human
neurologic disease, including prevalent diseases of the aged brain. SUR2 proteins are a …

The present study was designed to explore the mechanism of hesperidin action via the nitric
oxide pathway in the protection against ischemic reperfusion cerebral injury-induced …

Aging and degenerative diseases are associated with increased levels of reactive oxygen
species (ROS). ROS are mostly produced in mitochondria, and their levels increase with …

Neonatal hypoxia‐ischemia (HI) injury caused by oxygen deprivation is the most common
cause of mortality and severe neurologic deficits in neonates. The present work evaluated …