Challenges in metabolomics-based tests, biomarkers revealed by metabolomic analysis, and the promise of the application of metabolomics in precision medicine

A Di Minno, M Gelzo, M Caterino, M Costanzo… - International Journal of …, 2022 - mdpi.com
Metabolomics helps identify metabolites to characterize/refine perturbations of biological
pathways in living organisms. Pre-analytical, analytical, and post-analytical limitations that …

Plant metabolism as studied by NMR spectroscopy

C Deborde, A Moing, L Roch, D Jacob, D Rolin… - Progress in nuclear …, 2017 - Elsevier
The study of plant metabolism impacts a broad range of domains such as plant cultural
practices, plant breeding, human or animal nutrition, phytochemistry and green …

Translational metabolomics: current challenges and future opportunities

FR Pinu, SA Goldansaz, J Jaine - Metabolites, 2019 - mdpi.com
Metabolomics is one of the latest omics technologies that has been applied successfully in
many areas of life sciences. Despite being relatively new, a plethora of publications over the …

Ultrafast 2D NMR: an emerging tool in analytical spectroscopy

P Giraudeau, L Frydman - Annual Review of Analytical …, 2014 - annualreviews.org
Two-dimensional nuclear magnetic resonance (2D NMR) spectroscopy is widely used in
chemical and biochemical analyses. Multidimensional NMR is also witnessing increased …

NMR-based metabolomics and fluxomics: developments and future prospects

P Giraudeau - Analyst, 2020 - pubs.rsc.org
NMR spectroscopy is an essential analytical technique in metabolomics and fluxomics
workflows, owing to its high structural elucidation capabilities combined with its intrinsic …

Quantitative NMR spectroscopy of complex mixtures

P Giraudeau - Chemical Communications, 2023 - pubs.rsc.org
Complex mixtures are ubiquitous in many branches of chemistry, be it a complex
pharmaceutical formulation, a collection of biofluids analysed in a metabolomics workflow …

Challenges and perspectives in quantitative NMR

P Giraudeau - Magnetic Resonance in Chemistry, 2017 - Wiley Online Library
This perspective article summarizes, from the author's point of view at the beginning of 2016,
the major challenges and perspectives in the field of quantitative NMR. The key concepts in …

Multidimensional approaches to NMR-based metabolomics

K Bingol, R Brüschweiler - Analytical chemistry, 2014 - ACS Publications
The field of metabolomics, which is also referred to as metabonomics, has gained significant
attention over the recent past as it is developing rapidly as a powerful way to …

[HTML][HTML] Two dimensional NMR spectroscopic approaches for exploring plant metabolome: A review

EA Mahrous, MA Farag - Journal of advanced research, 2015 - Elsevier
Today, most investigations of the plant metabolome tend to be based on either nuclear
magnetic resonance (NMR) spectroscopy or mass spectrometry (MS), with or without …

Evaluation of fast 2D NMR for metabolomics

AL Guennec, P Giraudeau, S Caldarelli - Analytical chemistry, 2014 - ACS Publications
Two-dimensional nuclear magnetic resonance (2D NMR) is increasingly explored as a tool
for metabolomics because of its superior resolution compared to one-dimensional NMR (1D …