TRPM7, a divalent cation-selective channel with kinase domains, has been widely reported
to potentially affect cancers. In this study, we conducted multiple bioinformatic analyses …

Recent advances in the understanding of the molecular mechanisms underlying cancer
progression have led to the development of novel therapeutic targeting strategies. Aberrant …

Mechanosensitive ion channels comprise a broad group of proteins that sense mechanical
extracellular and intracellular changes, translating them into cation influx to adapt and …

O-GlcNAcylation is a post-translational modification occurring on serine/threonine residues
of nuclear and cytoplasmic proteins, mediated by the enzymes OGT and OGA which …

Abstract Background N6-methyladenosine (m6A) modification plays key roles in tumor
progression. LncRNA deoxyguanosine kinase antisense RNA 1 (DGUOK-AS1) has been …

Phosphatases of regenerating liver (PRL-1, PRL-2, PRL-3; also known as PTP4A1, PTP4A2,
PTP4A3, respectively) control intracellular magnesium levels by interacting with the CNNM …

Protein O-GlcNAcylation plays critical roles in many cellular events, and its dysregulation is
related to multiple diseases. Integrating bioorthogonal chemistry and multiplexed …

The transient melastatin receptor potential (TRPM) ion channel subfamily functions as
cellular sensors and transducers of critical biological signal pathways by regulating ion …

The transport of proteins between the different cellular compartments and the cell surface is
governed by the secretory pathway. Alternatively, unconventional secretion pathways have …

Simple Summary Breast cancer is the most frequently diagnosed malignant tumor and the
second leading cause of cancer death in women worldwide. The risk of developing breast …