Solubility is not to be confused with the ability to dissolve or liquefy a substance, since this
process may occur not only because of dissolution but also because of a chemical reaction …

During drug discovery and development, these is estimated 40% to 70% of incidence of
delay or failure for new chemical entities and major reason behind it is poor …

The solubility and dissolution enhancement of the poorly soluble drug ketoprofen (KTO) in
polymer blends prepared by hot melt extrusion was studied using two different screw …

Dissolution of poorly water-soluble active pharmaceutical ingredients (APIs) in polymeric
melts plays an important role in the manufacturing of solid dispersions and solid solutions …

It has been observed that most of the chemical entities have high lipophilicity and poor
aqueous solubility, which result in poor bioavailability. In order to improve the bioavailability …

Ketoprofen granules were prepared by surfactant-assisted wet granulation (SAWG) using
different concentrations of Soluplus®, polyethylene glycol (PEG) 6000 and 4000 grades and …

In recent times, a large number of studies concerning the improvement of the dissolution rate
of poorly watersoluble drugs is focused on the application of various porous materials as the …

Solubility enhancement holds signi cant importance in the eld of pharmaceutical research as
it aims to augment the solubility and bioavailability of drugs that possess low solubility …

In recent times, a large number of studies concerning the improvement of the dissolution rate
of poorly water-soluble drugs are focused on the application of various porous materials as …

Liquid solid compact technology is a novel approach to enhance bioavailability of a BCS
class II drug by improving its solubility and dissolution rate of the drug. Liquisols are the …