Fairly soluble drugs in gastrointestinal (GI) media exhibit complete oral absorption, and thus
good bioavailability. About 40% of drugs are not soluble in water in practice and therefore …

Inflammation and infection are two main factors predisposing a wound to become a chronic
one. Degradable wound dressings involving the controlled release of suitable drugs at the …

The main cause of failure of angioplasty stenting is restenosis due to neointimal hyperplasia,
a too high proliferation of smooth muscle cells (SMC). The local and sustained delivery of …

Multilayer nanofibrous scaffolds are gaining great attention in biomedical fields especially as
tissue regeneration materials as well as drug delivery devices. Herein, we report the unique …

Biodegradable wound dressing of poly glycerol sebacate/poly hydroxy butyrate was
fabricated via the coaxial electrospinning process. Simvastatin and ciprofloxacin were …

The aim of this study was to develop hydroxypropyl methyl cellulose (HPMC)/chitosan gel
containing polymeric micelles loaded with simvastatin (Sim) and evaluates its wound …

Liver cancer is a leading cause of death related to cancer worldwide. Poly (dl-lactide-co-
glycolide)(PLGA) nanoparticles provide prolonged blood residence time and sustained drug …

The aim of this study was to prepare and evaluate simvastatin (SIM) loaded elastic
provesicular systems for effective topical wound management. SIM provesicles were …

The objective of the present investigation was to study the effect of eutectic formation on in
vitro dissolution of simvastatin (SIM) released from mixtures with acetylsalicylic acid (ASA) …

The objective of this study was to use low viscosity grade hydroxypropyl methyl cellulose
(Methocel® E3 LV and Methocel® E5 LV) to enhance the solubility and dissolution of poorly …