Visible-to-NIR-light activated release: from small molecules to nanomaterials

R Weinstain, T Slanina, D Kand, P Klan - Chemical reviews, 2020 - ACS Publications
Photoactivatable (alternatively, photoremovable, photoreleasable, or photocleavable)
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …

Combination of light and Ru (II) polypyridyl complexes: Recent advances in the development of new anticancer drugs

L Conti, E Macedi, C Giorgi, B Valtancoli… - Coordination Chemistry …, 2022 - Elsevier
The increasing impact of cancer on worldwide mortality makes the research of novel
chemotherapeutic agents a current and challenging issue. In the recent years, transition …

Metal complexes for therapeutic applications

J Karges, RW Stokes, SM Cohen - Trends in chemistry, 2021 - cell.com
Metal complexes have been widely used for applications in the chemical and physical
sciences due to their unique electronic and stereochemical properties. For decades the use …

Ultra-efficient antibacterial system based on photodynamic therapy and CO gas therapy for synergistic antibacterial and ablation biofilms

W Ma, X Chen, L Fu, J Zhu, M Fan, J Chen… - … applied materials & …, 2020 - ACS Publications
In recent years, with the emergence of various kinds of drug-resistant bacteria, existing
antibiotics have become inefficient in killing these bacteria, and the formation of biofilms has …

Development of triggerable, trackable, and targetable carbon monoxide releasing molecules

LS Lazarus, AD Benninghoff… - Accounts of chemical …, 2020 - ACS Publications
Conspectus Carbon monoxide (CO) is a gaseous signaling molecule produced in humans
via the breakdown of heme in an O2-dependent reaction catalyzed by heme oxygenase …

Controlled therapeutic delivery of CO from carbon monoxide-releasing molecules (CORMs)

HI Choi, A Zeb, MS Kim, I Rana, N Khan… - Journal of Controlled …, 2022 - Elsevier
Carbon monoxide (CO) has been regarded as a “silent killer” for its toxicity toward biological
systems. However, a low concentration of endogenously produced CO has shown a number …

A prospective strategy leveraging nanomedicine for cancer therapy: pouring ferroptosis on apoptosis

Y Xia, J Zhang, G Liu - Nano Today, 2023 - Elsevier
As a fundamental process of the programmed cell death, apoptosis has endowed
nanomedicine broad horizons to treat tumor. However, apoptosis-resistance elicited by …

Activation of carbon dioxide by 9-carbene-9-borafluorene monoanion: carbon monoxide releasing transformation of trioxaborinanone to luminescent dioxaborinanone

KE Wentz, A Molino, LA Freeman… - Journal of the …, 2022 - ACS Publications
The first structurally characterized example of a trioxaborinanone (2) is produced by the
reaction of a 9-carbene-9-borafluorene monoanion and carbon dioxide. When compound 2 …

[HTML][HTML] Organic carbon monoxide prodrug, BW-CO-111, in protection against chemically-induced gastric mucosal damage

D Bakalarz, M Surmiak, X Yang, D Wójcik… - … Pharmaceutica Sinica B, 2021 - Elsevier
Metal-based carbon monoxide (CO)-releasing molecules have been shown to exert anti-
inflammatory and anti-oxidative properties maintaining gastric mucosal integrity. We are …

Towards “CO in a pill”: Pharmacokinetic studies of carbon monoxide prodrugs in mice

M Wang, X Yang, Z Pan, Y Wang, LK De La Cruz… - Journal of Controlled …, 2020 - Elsevier
Carbon monoxide (CO) is a known endogenous signaling molecule with potential
therapeutic indications in treating inflammation, cancer, neuroprotection, and sickle cell …