Active experience, not time, determines within-day representational drift in dorsal CA1

D Khatib, A Ratzon, M Sellevoll, O Barak, G Morris… - Neuron, 2023 - cell.com
Memories of past events can be recalled long after the event, indicating stability. But new
experiences are also integrated into existing memories, indicating plasticity. In the …

Building and breaking the chain: A model of reward prediction error integration and segmentation of memory

N Rouhani, D Clewett, JW Antony - Journal of Cognitive …, 2024 - direct.mit.edu
Prediction errors drive reinforcement learning and organize episodic memory into distinct
contexts, but do these effects interact? Here, we review the roles of midbrain dopamine, the …

Remapping revisited: how the hippocampus represents different spaces

AA Fenton - Nature Reviews Neuroscience, 2024 - nature.com
The representation of distinct spaces by hippocampal place cells has been linked to
changes in their place fields (the locations in the environment where the place cells …

Adult-born granule cells facilitate remapping of spatial and non-spatial representations in the dentate gyrus

SN Tuncdemir, AD Grosmark, H Chung, VM Luna… - Neuron, 2023 - cell.com
Adult-born granule cells (abGCs) have been implicated in memory discrimination through a
neural computation known as pattern separation. Here, using in vivo Ca 2+ imaging, we …

[HTML][HTML] Perpetual step-like restructuring of hippocampal circuit dynamics

ZS Zheng, R Huszár, T Hainmueller, M Bartos… - Cell reports, 2024 - cell.com
Summary Representation of the environment by hippocampal populations is known to drift
even within a familiar environment, which could reflect gradual changes in single-cell activity …

Novel off-context experience constrains hippocampal representational drift

G Elyasaf, A Rubin, Y Ziv - Current Biology, 2024 - cell.com
The hippocampus forms unique neural representations for distinct experiences, supporting
the formation of different memories. 1, 2, 3, 4, 5, 6 Hippocampal representations gradually …

NMDA receptors regulate the firing rate set point of hippocampal circuits without altering single-cell dynamics

A Ruggiero, LR Heim, L Susman, D Hreaky, I Shapira… - Neuron, 2025 - cell.com
Understanding how neuronal circuits stabilize their activity is a fundamental yet poorly
understood aspect of neuroscience. Here, we show that hippocampal network properties …

Time and experience are independent determinants of representational drift in CA1

JQ Lee, MP Brandon - Neuron, 2023 - cell.com
Time and experience are independent determinants of representational drift in CA1: Neuron
Skip to Main Content Advertisement Neuron This journal offers authors two options (open access …

Sensory experience steers representational drift in mouse visual cortex

J Bauer, U Lewin, E Herbert, J Gjorgjieva… - Nature …, 2024 - nature.com
Representational drift—the gradual continuous change of neuronal representations—has
been observed across many brain areas. It is unclear whether drift is caused by synaptic …

Context and space coding in mossy cell population activity

LW Huang, F Torelli, HL Chen, M Bartos - Cell Reports, 2024 - cell.com
The dentate gyrus plays a key role in the discrimination of memories by segregating and
storing similar episodes. Whether hilar mossy cells, which constitute a major excitatory …