Polymersome-based protein drug delivery–quo vadis?
MG Gouveia, JP Wesseler, J Ramaekers… - Chemical Society …, 2023 - pubs.rsc.org
Protein-based therapeutics are an attractive alternative to established therapeutic
approaches and represent one of the fastest growing families of drugs. While many of these …
approaches and represent one of the fastest growing families of drugs. While many of these …
Advanced liposome and polymersome-based drug delivery systems: Considerations for physicochemical properties, targeting strategies and stimuli-sensitive …
Liposomes and polymersomes are colloidal vesicles that are self-assembled from lipids and
amphiphilic polymers, respectively. Because of their ability to encapsulate both hydrophilic …
amphiphilic polymers, respectively. Because of their ability to encapsulate both hydrophilic …
Enzyme-mediated nitric oxide production in vasoactive erythrocyte membrane-enclosed coacervate protocells
The design and construction of synthetic therapeutic protocells capable of establishing
cognate chemical communication channels with living cells is an important challenge for …
cognate chemical communication channels with living cells is an important challenge for …
Optically active nanomaterials and its biosensing applications—a review
This article discusses optically active nanomaterials and their optical biosensing
applications. In addition to enhancing their sensitivity, these nanomaterials also increase …
applications. In addition to enhancing their sensitivity, these nanomaterials also increase …
Photoresponsive DNA materials and their applications
Photoresponsive nucleic acids attract growing interest as functional constituents in materials
science. Integration of photoisomerizable units into DNA strands provides an ideal handle …
science. Integration of photoisomerizable units into DNA strands provides an ideal handle …
Polymersomes for therapeutic delivery of protein and nucleic acid macromolecules: from design to therapeutic applications
Macromolecule-based therapeutic agents, particularly proteins, antigens, monoclonal
antibodies, transcription factors, nucleic acids, and gene editing enzymes, have the potential …
antibodies, transcription factors, nucleic acids, and gene editing enzymes, have the potential …
Amino acid coordination driven self‐assembly for enhancing both the biological stability and tumor accumulation of curcumin
Y Li, Q Zou, C Yuan, S Li, R Xing… - Angewandte Chemie …, 2018 - Wiley Online Library
Clinical translation of curcumin has been highly obstructed by the rapid degradation and
poor tissue absorption of this agent. Herein, we report on the generation of supramolecular …
poor tissue absorption of this agent. Herein, we report on the generation of supramolecular …
Twenty-five years of polymersomes: lost in translation?
Soon after the discovery of polymeric vesicles (polymersomes), reports of their high
membrane stability raised hopes for the development of next generation vesicles for drug …
membrane stability raised hopes for the development of next generation vesicles for drug …
Self-assembled polymeric vesicles: Focus on polymersomes in cancer treatment
The progress in advanced materials using nanoscale components can be conducted by an
innovative idea involving combining nanotechnology approaches with supramolecular …
innovative idea involving combining nanotechnology approaches with supramolecular …
Dynamic metastable polymersomes enable continuous flow manufacturing
Polymersomes are polymeric analogues of liposomes with exceptional physical and
chemical properties. Despite being dubbed as next-generation vesicles since their inception …
chemical properties. Despite being dubbed as next-generation vesicles since their inception …