Major depressive disorder (MDD) is a highly heterogeneous mental disorder, and its
complex etiology and unclear mechanism are great obstacles to the diagnosis and treatment …

Background Cognitive behavioral therapy (CBT) is a first-line psychotherapeutic treatment
that has been recommended for psychiatric disorders. Prior neuroimaging studies have …

The neuroimaging is an important tool for understanding the biomarkers and predicting
treatment responses in major depressive disorder (MDD). The potential biomarkers and …

Stroke is a leading cause of mortality and a major cause of disability worldwide. A significant
number of stroke survivors suffer from depression, impeding the activities of daily living and …

Affective disorders are associated with maladaptive emotion regulation strategies. In
particular, the left more than the right ventrolateral prefrontal cortex (vlPFC) may insufficiently …

Background. Aberrant activity of the subcallosal cingulate (SCC) is a common theme across
pharmacologic treatment efficacy prediction studies. The functioning of the SCC in …

Background Previous studies have found that transcutaneous auricular vagus nerve
stimulation (taVNS) is clinically effective in the treatment of major depressive disorder …

BackgroundElectroconvulsive therapy (ECT) is the most effective antidepressant treatment
for severe depression. Although recent structural magnetic resonance imaging (MRI) studies …

Abstract Treatment outcomes widely vary for individuals diagnosed with major depressive
disorder, implicating a need for deeper understanding of the biological mechanisms …

BackgroundCognitive behavioral therapy (CBT) is an effective treatment for patients with
social anxiety disorder (SAD) or major depressive disorder (MDD), yet there is variability in …