Acoustic tweezers for the life sciences

A Ozcelik, J Rufo, F Guo, Y Gu, P Li, J Lata, TJ Huang - Nature methods, 2018 - nature.com
Acoustic tweezers are a versatile set of tools that use sound waves to manipulate
bioparticles ranging from nanometer-sized extracellular vesicles to millimeter-sized …

Fantastic voyage of nanomotors into the cell

PL Venugopalan, B Esteban-Fernández de Ávila… - ACS …, 2020 - ACS Publications
Richard Feynman's 1959 vision of controlling devices at small scales and swallowing the
surgeon has inspired the science-fiction Fantastic Voyage film and has played a crucial role …

Adherens junctions as molecular regulators of emergent tissue mechanics

O Campàs, I Noordstra, AS Yap - Nature Reviews Molecular Cell …, 2024 - nature.com
Tissue and organ development during embryogenesis relies on the collective and
coordinated action of many cells. Recent studies have revealed that tissue material …

Biophysics in tumor growth and progression: from single mechano-sensitive molecules to mechanomedicine

Y Xin, K Li, M Huang, C Liang, D Siemann, L Wu, Y Tan… - Oncogene, 2023 - nature.com
Evidence from physical sciences in oncology increasingly suggests that the interplay
between the biophysical tumor microenvironment and genetic regulation has significant …

A robot-assisted acoustofluidic end effector

J Durrer, P Agrawal, A Ozgul, SCF Neuhauss… - Nature …, 2022 - nature.com
Liquid manipulation is the foundation of most laboratory processes. For macroscale liquid
handling, both do-it-yourself and commercial robotic systems are available; however, for …

Mechanics of the cellular microenvironment as probed by cells in vivo during zebrafish presomitic mesoderm differentiation

A Mongera, M Pochitaloff, HJ Gustafson… - nature materials, 2023 - nature.com
Tissue morphogenesis, homoeostasis and repair require cells to constantly monitor their
three-dimensional microenvironment and adapt their behaviours in response to local …

Mechanisms and impact of altered tumour mechanics

H Mohammadi, E Sahai - Nature cell biology, 2018 - nature.com
The physical characteristics of tumours are intricately linked to the tumour phenotype and
difficulties during treatment. Many factors contribute to the increased stiffness of tumours; …

Broken detailed balance and non-equilibrium dynamics in living systems: a review

FS Gnesotto, F Mura, J Gladrow… - Reports on Progress in …, 2018 - iopscience.iop.org
Living systems operate far from thermodynamic equilibrium. Enzymatic activity can induce
broken detailed balance at the molecular scale. This molecular scale breaking of detailed …

Viscoelastic hydrogels for 3D cell culture

O Chaudhuri - Biomaterials science, 2017 - pubs.rsc.org
In tissues, many cells are surrounded by and interact with a three-dimensional soft
extracellular matrix (ECM). Both the physical and biochemical properties of the ECM play a …

Signatures of Majorana fermions in hybrid superconductor-semiconductor nanowire devices

V Mourik, K Zuo, SM Frolov, SR Plissard… - Science, 2012 - science.org
Majorana fermions are particles identical to their own antiparticles. They have been
theoretically predicted to exist in topological superconductors. Here, we report electrical …